YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|157833802, gi...
Organism:	Escherichia coli
Length:	180 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157833802, gi....

Description	E-value	Query Range	Subject Range
gi\|74020145, gi\|... - gi\|74020145\|ref\|ZP_00690750.1\| Methylated-DNA-(protein)-cysteine S-methyltransferase [Burkholderia a...	217.0	[0..1]	[178..189]
gi\|63257301, gi\|... - gi\|66046594\|ref\|YP_236435.1\| methylated-DNA-[protein]-cysteine S-methyltransferase [Pseudomonas syri...	216.0	[0..1]	[177..200]
gi\|238783968, gi... - gi\|77958481\|ref\|ZP_00822514.1\| COG2169: Adenosine deaminase [Yersinia bercovieri ATCC 43970], gi\|238...	216.0	[0..1]	[178..192]
gi\|71554218, gi\|... - gi\|71733665\|ref\|YP_275444.1\| ADA regulatory protein [Pseudomonas syringae pv. phaseolicola 1448A], g...	216.0	[0..1]	[177..184]
gi\|186467753, gi... - gi\|23130248\|ref\|ZP_00112065.1\| COG2169: Adenosine deaminase [Nostoc punctiforme PCC 73102], gi\|18668...	216.0	[0..1]	[174..178]
gi\|77960030, gi\|... - gi\|77960030\|ref\|ZP_00823930.1\| COG2169: Adenosine deaminase [Yersinia mollaretii ATCC 43969], gi\|238...	215.0	[0..1]	[178..192]
gi\|78067977, gi\|... - gi\|78067977\|ref\|YP_370746.1\| bifunctional DNA-O6-methylguanine--protein-cysteine S-methyltransferase...	214.0	[0..1]	[179..172]
gi\|91689749, gi\|... - gi\|91785795\|ref\|YP_561001.1\| AraC family transcriptional regulator [Burkholderia xenovorans LB400], ...	214.0	[0..1]	[175..183]
gi\|67660419, gi\|... - gi\|67660419\|ref\|ZP_00457766.1\| Methylated-DNA-[protein]-cysteine S-methyltransferase [Burkholderia c... gi\|67666819, gi\|... - gi\|67666819\|ref\|ZP_00464058.1\| Methylated-DNA-[protein]-cysteine S-methyltransferase [Burkholderia c...	212.0	[0..1]	[179..172]
gi\|77459163, gi\|... - gi\|77459163\|ref\|YP_348669.1\| AraC family transcriptional regulator [Pseudomonas fluorescens Pf0-1], ...	212.0	[0..1]	[175..179]

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Predicted Domain #1

Region A:
Residues: [1-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAKQFRHGG ENLAVRYALA DCELGRCLVA ESERGICAIL LGDDDATLIS ELQQMFPAAD  60
   61 NAPADLMFQQ HVREVIASLN QRDTPLTLPL DIRGTAFQQQ VWQALRTIPC GETVSYQQLA 120
  121 NAIGKPKAVR AVASACAANK LAIVIPCHRV VRGDGSLSGY RWGVSRKAQL LRREAENEER 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.30103
Match:	1sfeA
Description:	ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methylated-DNA-[protein]-cysteine S-methyltransferase activity	3.81641972619245	bayes_pls_golite062009
S-methyltransferase activity	2.66007025371147	bayes_pls_golite062009
catalytic activity	1.90838528948382	bayes_pls_golite062009
DNA binding	1.54553435062678	bayes_pls_golite062009
nucleic acid binding	1.49720271661049	bayes_pls_golite062009
binding	1.30758209326705	bayes_pls_golite062009
transcription regulator activity	1.26332746912934	bayes_pls_golite062009
transferase activity	1.22815682532854	bayes_pls_golite062009
methyltransferase activity	1.14625481859451	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.13184530961695	bayes_pls_golite062009
transcription factor activity	0.99095733801135	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: