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View Structure Prediction Details

Protein: gi|3318842, gi|3...
Organism: Homo sapiens
Length: 224 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|3318842, gi|3....

Description E-value Query
Range
Subject
Range
gi|114565483, gi... - gi|114621471|ref|XP_001143738.1| PREDICTED: similar to KIAA0106 [Pan troglodytes], gi|114565483|ref|...
gi|168274370 - gi|168274370|dbj|BAG09605.1| peroxiredoxin-6 [synthetic construct]
PRDX6 - peroxiredoxin 6
219.0 [0..1] [224..1]
PRDX6_PONPY - Peroxiredoxin-6 - Pongo pygmaeus (Orangutan)
PRDX6_PONAB - Peroxiredoxin-6 OS=Pongo abelii GN=PRDX6 PE=2 SV=3
218.0 [0..1] [224..1]
PRDX6_BOVIN - Peroxiredoxin-6 OS=Bos taurus GN=PRDX6 PE=1 SV=3
217.0 [0..1] [224..1]
CCDS1307.1_1 - null
gi|109019544 - gi|109019544|ref|XP_001101473.1| PREDICTED: peroxiredoxin 6 [Macaca mulatta]
217.0 [0..1] [224..1]
PRDX6_RAT - Peroxiredoxin-6 OS=Rattus norvegicus GN=Prdx6 PE=1 SV=3
217.0 [0..1] [224..1]
gi|83012875, gi|... - gi|83012875|ref|XP_923578.1| PREDICTED: similar to Peroxiredoxin 6 (Antioxidant protein 2) (1-Cys pe...
216.0 [0..1] [224..1]
PRDX6_MACFA - Peroxiredoxin-6 OS=Macaca fascicularis GN=PRDX6 PE=2 SV=3
215.0 [0..1] [224..1]

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Predicted Domain #1
Region A:
Residues: [1-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGGLLLGDV APNFEANTTV GRIRFHDFLG DSWGILFSHP RDFTPVXTTE LGRAAKLAPE  60
   61 FAKRNVKLIA LSIDSVEDHL AWSKDINAYN SEEPTEKLPF PIIDDRNREL AILLGMLDPA 120
  121 EKDEKGMPVT ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD 180
  181 WKDGDSVMVL PTIPEEEAKK LFPKGVFTKE LPSGKKYLRY TPQP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.154902
Match: 1prxA
Description: HorF6 peroxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alkyl hydroperoxide reductase activity 4.29610283853788 bayes_pls_golite062009
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
selenium binding 2.35334277406288 bayes_pls_golite062009
transcription regulator activity 2.30799114442278 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
transferase activity 1.26687471229876 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
NADH dehydrogenase activity 0.23291471505999 bayes_pls_golite062009
copper ion binding 0.178842772364502 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 0.16328723676608 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 0.0434052164026002 bayes_pls_golite062009

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