YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1943036, gi\|1...
Organism:	Escherichia coli
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1943036, gi|1....

Description	E-value	Query Range	Subject Range
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	311.0	[0..2]	[280..56]
gi\|20515183, gi\|... - gi\|20806727\|ref\|NP_621898.1\| transcriptional regulator [Thermoanaerobacter tengcongensis MB4], gi\|20... gi\|20806727 - gi\|20806727\|ref\|NP_621898.1\| Transcriptional regulator [Thermoanaerobacter tengcongensis MB4] gi\|254478068, gi... - gi\|254478068\|ref\|ZP_05091451.1\| Periplasmic binding proteins and sugar binding domain of the LacI fa...	307.0	[0..2]	[280..56]
gi\|37200774, gi\|... - gi\|37676233\|ref\|NP_936629.1\| transcriptional regulator [Vibrio vulnificus YJ016], gi\|37200774\|dbj\|BA...	305.0	[0..1]	[279..54]
gi\|27366525, gi\|... - gi\|27366525\|ref\|NP_762052.1\| transcriptional regulator [Vibrio vulnificus CMCP6], gi\|27358091\|gb\|AAO...	302.0	[0..1]	[279..54]
PURR_YERPE - HTH-type transcriptional repressor PurR OS=Yersinia pestis GN=purR PE=3 SV=1 gi\|45441965, gi\|... - gi\|45441965\|ref\|NP_993504.1\| DNA-binding transcriptional repressor PurR [Yersinia pestis biovar Micr... gi\|22125842, gi\|... - gi\|22125842\|ref\|NP_669265.1\| DNA-binding transcriptional repressor PurR [Yersinia pestis KIM], gi\|21... PURR_YERPG - HTH-type transcriptional repressor PurR OS=Yersinia pestis bv. Antiqua (strain Angola) GN=purR PE=3 ... gi\|115348089, gi... - gi\|218929478\|ref\|YP_002347353.1\| DNA-binding transcriptional repressor PurR [Yersinia pestis CO92], ... PURR_YERPY - HTH-type transcriptional repressor PurR OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) G... PURR_YERPS - HTH-type transcriptional repressor PurR OS=Yersinia pseudotuberculosis serotype I (strain IP32953) G... PURR_YERPB - HTH-type transcriptional repressor PurR OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN... gi\|165913450, gi... - gi\|89103799\|ref\|ZP_01176363.1\| COG1609: Transcriptional regulators [Yersinia pestis biovar Orientali... PURR_YERPN - HTH-type transcriptional repressor PurR OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=purR PE=... gi\|229837912, gi... - gi\|229837912\|ref\|ZP_04458071.1\| DNA-binding transcriptional repressor, hypoxanthine-binding [Yersini... gi\|229701961, gi... - gi\|229895073\|ref\|ZP_04510250.1\| DNA-binding transcriptional repressor, hypoxanthine-binding [Yersini... gi\|229898475, gi... - gi\|229898475\|ref\|ZP_04513621.1\| DNA-binding transcriptional repressor, hypoxanthine-binding [Yersini... gi\|149292115, gi... - gi\|149365702\|ref\|ZP_01887737.1\| purine nucleotide synthesis repressor [Yersinia pestis CA88-4125], g... PURR_YERPP - HTH-type transcriptional repressor PurR OS=Yersinia pestis (strain Pestoides F) GN=purR PE=3 SV=1 gi\|165926499, gi... - gi\|165926499\|ref\|ZP_02222331.1\| purine nucleotide synthesis repressor [Yersinia pestis biovar Orient... PURR_YERPS - HTH-type transcriptional repressor PurR OS=Yersinia pseudotuberculosis GN=purR PE=3 SV=1 gi\|165990377, gi... - gi\|166010675\|ref\|ZP_02231573.1\| purine nucleotide synthesis repressor [Yersinia pestis biovar Antiqu... gi\|166211173, gi... - gi\|166211173\|ref\|ZP_02237208.1\| purine nucleotide synthesis repressor [Yersinia pestis biovar Antiqu... gi\|166959013, gi... - gi\|167422201\|ref\|ZP_02313954.1\| purine nucleotide synthesis repressor [Yersinia pestis biovar Orient... gi\|167425063, gi... - gi\|167425063\|ref\|ZP_02316816.1\| purine nucleotide synthesis repressor [Yersinia pestis biovar Mediae... gi\|167469396 - gi\|167469396\|ref\|ZP_02334100.1\| purine nucleotide synthesis repressor [Yersinia pestis FV-1] PURR_YERP3 - HTH-type transcriptional repressor PurR OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 3175...	302.0	[0..1]	[289..53]
gi\|91224726, gi\|... - gi\|91224726\|ref\|ZP_01259986.1\| ribose operon repressor [Vibrio alginolyticus 12G01], gi\|91190272\|gb\|...	301.0	[0..1]	[281..54]
gi\|238719809, gi... - gi\|77961722\|ref\|ZP_00825554.1\| COG1609: Transcriptional regulators [Yersinia mollaretii ATCC 43969],...	300.0	[0..1]	[289..53]
gi\|75190697 - gi\|75190697\|ref\|ZP_00703964.1\| COG1609: Transcriptional regulators [Escherichia coli E24377A]	300.0	[0..1]	[289..36]
gi\|77959193, gi\|... - gi\|77959193\|ref\|ZP_00823215.1\| COG1609: Transcriptional regulators [Yersinia bercovieri ATCC 43970],...	300.0	[0..1]	[289..53]
gi\|76797419, gi\|... - gi\|76797419\|ref\|ZP_00779738.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti... gi\|241882990, gi... - gi\|241904637\|ref\|ZP_04789316.1\| transcriptional regulator, LacI family [Thermoanaerobacter brockii s...	300.0	[0..2]	[280..56]

Back

Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLKVNHTKSI GLLATSSEAA YFAEIIEAVE KNCFQKGYTL ILGNAWNNLE KQRAYLSMMA  60
   61 QKRVDGLLVM CSEYPEPLLA MLEEYRHIPM VVMDWGEAKA DFTDAVIDNA FEGGYMAGRY 120
  121 LIERGHREIG VIPGPLERNT GAGRLAGFMK AMEEAMIKVP ESWIVQGDFE PESGYRAMQQ 180
  181 ILSQPHRPTA VFCGGDIMAM GALCAADEMG LRVPQDVSLI GYDNVRNARY FTPALTTIHQ 240
  241 PKDSLGETAF NMLLDRIVNK REEPQSIEVH PRLIERRSVA DGPFRDYRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.522879
Match:	1dbqA
Description:	Purine repressor (PurR), C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.03730517010624	bayes_pls_golite062009
DNA binding	2.13752511265098	bayes_pls_golite062009
transcription factor activity	2.10452652023643	bayes_pls_golite062009
nucleic acid binding	2.05471649974481	bayes_pls_golite062009
binding	1.58080550382179	bayes_pls_golite062009
signal transducer activity	0.11302624216037	bayes_pls_golite062009
molecular transducer activity	0.11302624216037	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: