YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|2914394
Organism:	Homo sapiens
Length:	236 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2914394.

Description	E-value	Query Range	Subject Range
gi\|108401 - pir\|\|S12136 somatotropin receptor precursor - pig gi\|55742682 - ref\|NP_999419.1\| growth hormone receptor [Sus scrofa] GHR_PIG - Growth hormone receptor OS=Sus scrofa GN=GHR PE=1 SV=1	213.0	[0..1]	[236..19]
GHR_CANLF - Growth hormone receptor OS=Canis lupus familiaris GN=GHR PE=2 SV=1	211.0	[0..1]	[236..19]
gi\|225853 - gi\|225853\|prf\|\|1401239A growth hormone receptor	211.0	[0..1]	[236..19]
GHR_AILME - Growth hormone receptor OS=Ailuropoda melanoleuca GN=GHR PE=2 SV=1	208.0	[0..2]	[236..20]
GHR_RAT - Growth hormone receptor OS=Rattus norvegicus GN=Ghr PE=1 SV=1	205.0	[0..1]	[236..19]
GHR_PAPAN - Growth hormone receptor OS=Papio anubis GN=GHR PE=2 SV=1	203.0	[0..1]	[236..19]
gi\|114600435 - gi\|114600435\|ref\|XP_526938.2\| PREDICTED: hypothetical protein [Pan troglodytes]	202.0	[0..1]	[236..19]
gi\|183171, gi\|107699 - gi\|183171\|gb\|AAA52555.1\| growth hormone receptor, pir\|\|A33991 somatotropin receptor precursor - huma...	202.0	[0..1]	[236..19]

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Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSGSEATAAI LSRAPWSLQS VNPGLKTNSS GEPKFTKCRS PERETFSCHW TDEVHHGTKN  60
   61 EGPIQLFYTR RNTQEWTQEW KECPDYVSAG ENSCYFNSSF TSIAIPYCIK LTSNGGTVDE 120
  121 KCFSVDEIVQ PDPPIALNWT LLNVSLTGIH ADIQVRWEAP RNADIQKGWM VLEYELQYKE 180
  181 VNETKWKMMD PILTTSVPVY SLKVDKEYEV RVRSKQRNSG NYGEFSEVLY VTLPQM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1a22B
Description:	Growth hormone receptor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits