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View Structure Prediction Details

Protein: gi|21748606
Organism: Homo sapiens
Length: 791 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|21748606.

Description E-value Query
Range
Subject
Range
gi|109114143, gi... - gi|109114143|ref|XP_001087204.1| PREDICTED: nuclear factor (erythroid-derived 2)-like 1 isoform 13 [...
0.0 [20..791] [1..772]
gi|114666372 - gi|114666372|ref|XP_001173202.1| PREDICTED: nuclear factor (erythroid-derived 2)-like 1 isoform 4 [P...
NFE2L1 - nuclear factor (erythroid-derived 2)-like 1
gi|168272888 - gi|168272888|dbj|BAG10283.1| nuclear factor erythroid 2-related factor 1 [synthetic construct]
0.0 [20..791] [1..772]
gi|55729299 - gi|55729299|emb|CAH91385.1| hypothetical protein [Pongo abelii]
NF2L1_PONAB - Nuclear factor erythroid 2-related factor 1 OS=Pongo abelii GN=NFE2L1 PE=2 SV=1
0.0 [20..791] [1..772]
gi|73966220, gi|... - gi|73966220|ref|XP_537663.2| PREDICTED: similar to Nuclear factor erythroid 2 related factor 1 (NF-E...
1.0E-98 [20..791] [1..781]
gi|47847522 - gi|47847522|dbj|BAD21433.1| mFLJ00380 protein [Mus musculus]
4.0E-98 [5..791] [12..767]
gi|542952, gi|14... - pir||A49672 transcription factor Nrf1 - human, gi|14714932|gb|AAH10623.1| NFE2L1 protein [Homo sapie...
gi|123995137, gi... - gi|123995137|gb|ABM85170.1| nuclear factor (erythroid-derived 2)-like 1 [synthetic construct], gi|12...
gi|114666378, gi... - gi|114666378|ref|XP_001173218.1| PREDICTED: nuclear factor (erythroid-derived 2)-like 1 isoform 6 [P...
9.0E-97 [20..791] [1..742]
NF2L1_CHICK - Nuclear factor erythroid 2-related factor 1 OS=Gallus gallus GN=NFE2L1 PE=2 SV=1
8.0E-94 [20..791] [1..772]

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Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVFWKILKTK KHKHSGPSAM LSLKKYLTEG LLQFTILLSL IGVRVDVDTY LTSQLPPLRE  60
   61 IILGPSSAYT QTQFHNLRNT LDGYGIHPKS IDLDNYFTAR RLLSQVRALD RFQVPTTEVN 120
  121 AWLVHRDPEG 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.236 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.323 a.25.1 Ferritin-like
View Download 0.420 a.74.1 Cyclin-like
View Download 0.235 a.29.2 Bromodomain
View Download 0.347 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #2
Region A:
Residues: [131-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVSGSQPNSG LALESSSGLQ DVTGPDNGVR ESETEQGFGE DLEDLGAVAP PVSGDLTKED  60
   61 IDLIDILWRQ DIDLGAGREV FDYSHRQKEQ DVEKELRDGG EQDTWAGEGA EALARNLLVD 120
  121 GETGESFPAQ VPSGEDQTAL SLEECLRLL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.321 N/A N/A a.1.1 Globin-like
View Download 0.295 N/A N/A d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.259 N/A N/A c.97.1 Cytidine deaminase-like
View Download 0.244 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.222 N/A N/A a.118.9 ENTH/VHS domain

Predicted Domain #3
Region A:
Residues: [280-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EATCPFGENA EFPADISSIT EAVPSESEPP ALQNNLLSPL LTGTESPFDL EQQWQDLMSI  60
   61 MEMQAMEVNT SASEILYSAP PGDPLSTNYS LAPNTPINQN VSLHQASLGG CSQDFLLFSP 120
  121 EVESLPVASS STLLPLAPSN STSLNSTFGS TNLTGLFFPP Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [441-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNGTANDTAG PELPDPLGGL LDEAMLDEIS LMDLAIEEGF NPVQASQLEE EFDSDSGLSL  60
   61 DSSHSPSSLS SSEGSSSSSS SSSSSSSSAS SSASSSFSEE GAVGYSSDSE TLDLEEAEGA 120
  121 VGYQPEYSKF CRMSYQDPAQ LSCLPYLEHV GHNHTYNMAP SALDSADLPP PSALKKGSKE 180
  181 KQADFLDKQM SRDEHRARAM KIPFTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [647-791]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKIINLPVEE FNELLSKYQL SEAQLSLIRD IRRRGKNKMA AQNCRKRKLD TILNLERDVE  60
   61 DLQRDKARLL REKVEFLRSL RQMKQKVQSL YQEVFGRLRD ENGRPYSPSQ YALQYAGDGS 120
  121 VLLIPRTMAD QQARRQERKP KDRRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle