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Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity. A process that directly activates any of the steps required for cell death by apoptosis. Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. The directed killing of a target cell by a leukocyte. Any process that stops, prevents or reduces the frequency, rate or extent of cell killing. Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity. Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity. Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. The process of protecting a cell from natural killer cell mediated cytotoxicity. Any process that stops, prevents or reduces the frequency, rate or extent of the innate immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of natural killer cell mediated cytotoxicity
Acc: GO:0045953
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
Synonyms:
  • negative regulation of NK cell mediated cytotoxicity
  • negative regulation of natural killer cell mediated cell killing
  • negative regulation of natural killer cell mediated cytolysis
  • down regulation of natural killer cell mediated cytotoxicity
  • negative regulation of NK cell mediated cytolysis
  • downregulation of natural killer cell mediated cytotoxicity
  • down-regulation of natural killer cell mediated cytotoxicity
  • inhibition of natural killer cell mediated cytotoxicity
  • negative regulation of NK cell mediated cell killing
  • negative regulation of natural killer cell mediated cell death
  • negative regulation of NK cell mediated cell death
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 18 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045953 - negative regulation of natural killer cell mediated cytotoxicity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle