From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.672494980621] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
late endosome | 1.1672E-5 | 2 | 22 | 2 | 6292 |
endosome | 2.2085E-4 | 2 | 94 | 2 | 6292 |
vacuolar proton-transporting V-type ATPase, V0 domain | 2.224E-3 | 2 | 7 | 1 | 6292 |
proton-transporting V-type ATPase, V0 domain | 2.224E-3 | 2 | 7 | 1 | 6292 |
vacuolar proton-transporting V-type ATPase complex | 4.7627E-3 | 2 | 15 | 1 | 6292 |
proton-transporting V-type ATPase complex | 4.7627E-3 | 2 | 15 | 1 | 6292 |
proton-transporting two-sector ATPase complex, proton-transporting domain | 6.0308E-3 | 2 | 19 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
vacuolar acidification | 1.3945E-5 | 2 | 24 | 2 | 6292 |
pH reduction | 1.3945E-5 | 2 | 24 | 2 | 6292 |
intracellular pH reduction | 1.3945E-5 | 2 | 24 | 2 | 6292 |
regulation of cellular pH | 1.5158E-5 | 2 | 25 | 2 | 6292 |
regulation of intracellular pH | 1.5158E-5 | 2 | 25 | 2 | 6292 |
regulation of pH | 2.0514E-5 | 2 | 29 | 2 | 6292 |
cellular monovalent inorganic cation homeostasis | 2.8346E-5 | 2 | 34 | 2 | 6292 |
monovalent inorganic cation homeostasis | 3.552E-5 | 2 | 38 | 2 | 6292 |
cellular cation homeostasis | 2.7588E-4 | 2 | 105 | 2 | 6292 |
cation homeostasis | 2.974E-4 | 2 | 109 | 2 | 6292 |
cellular chemical homeostasis | 3.5475E-4 | 2 | 119 | 2 | 6292 |
cellular ion homeostasis | 3.5475E-4 | 2 | 119 | 2 | 6292 |
cellular homeostasis | 3.6076E-4 | 2 | 120 | 2 | 6292 |
chemical homeostasis | 3.791E-4 | 2 | 123 | 2 | 6292 |
ion homeostasis | 3.791E-4 | 2 | 123 | 2 | 6292 |
homeostatic process | 4.1951E-3 | 2 | 408 | 2 | 6292 |
regulation of biological quality | 7.6561E-3 | 2 | 551 | 2 | 6292 |
monovalent inorganic cation transport | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
monovalent inorganic cation transmembrane transporter activity | 8.6451E-5 | 2 | 59 | 2 | 6292 |
inorganic cation transmembrane transporter activity | 2.5516E-4 | 2 | 101 | 2 | 6292 |
cation transmembrane transporter activity | 3.4879E-4 | 2 | 118 | 2 | 6292 |
ion transmembrane transporter activity | 5.3483E-4 | 2 | 146 | 2 | 6292 |
substrate-specific transmembrane transporter activity | 1.7943E-3 | 2 | 267 | 2 | 6292 |
transmembrane transporter activity | 2.3578E-3 | 2 | 306 | 2 | 6292 |
substrate-specific transporter activity | 2.8436E-3 | 2 | 336 | 2 | 6292 |
transporter activity | 4.1132E-3 | 2 | 404 | 2 | 6292 |
proton-transporting ATPase activity, rotational mechanism | 4.1283E-3 | 2 | 13 | 1 | 6292 |
cation-transporting ATPase activity | 5.0798E-3 | 2 | 16 | 1 | 6292 |
ATPase activity, coupled to transmembrane movement of ions | 9.1975E-3 | 2 | 29 | 1 | 6292 |