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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.981450006063]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
PEP8
  • endosome
  • retromer complex
    		•
  • protein retention in Golgi apparatus
  • retrograde transport, endosome to Golgi
    		•
  • protein transporter activity
    		•
    VPS35
  • endosome
  • retromer complex
    		•
  • protein retention in Golgi apparatus
  • retrograde transport, endosome to Golgi
    		•
  • protein binding
  • protein transporter activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    retromer complex 7.579E-7 2 6 2 6292
    endosome 2.2085E-4 2 94 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein retention in Golgi apparatus 3.9411E-6 2 13 2 6292
    protein localization in Golgi apparatus 3.9411E-6 2 13 2 6292
    retrograde transport, endosome to Golgi 8.6401E-6 2 19 2 6292
    maintenance of protein location in cell 1.5158E-5 2 25 2 6292
    maintenance of protein location 1.6421E-5 2 26 2 6292
    maintenance of location in cell 1.7735E-5 2 27 2 6292
    maintenance of location 1.9099E-5 2 28 2 6292
    endosome transport 6.6999E-5 2 52 2 6292
    protein localization in organelle 5.5711E-4 2 149 2 6292
    cellular protein localization 1.8898E-3 2 274 2 6292
    cellular macromolecule localization 2.0305E-3 2 284 2 6292
    protein localization 2.3118E-3 2 303 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein transporter activity 8.3521E-5 2 58 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle