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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.10374694631]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ARP2
  • mitochondrion
  • Arp2/3 protein complex
    		•
  • mitochondrion inheritance
  • actin filament organization
    		•
  • ATP binding
  • actin binding
  • structural constituent of cytoskeleton
    		•
    ARP3
  • Arp2/3 protein complex
    		•
  • mitochondrion inheritance
  • actin filament organization
    		•
  • ATP binding
  • actin binding
  • structural constituent of cytoskeleton
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Arp2/3 protein complex 1.0611E-6 2 7 2 6292
    actin cytoskeleton 1.8038E-4 2 85 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitochondrion inheritance 2.0514E-5 2 29 2 6292
    mitochondrion distribution 2.0514E-5 2 29 2 6292
    mitochondrion localization 2.1979E-5 2 30 2 6292
    organelle inheritance 4.7798E-5 2 44 2 6292
    actin filament organization 1.151E-4 2 68 2 6292
    organelle localization 1.8038E-4 2 85 2 6292
    actin cytoskeleton organization 3.1973E-4 2 113 2 6292
    actin filament-based process 3.4287E-4 2 117 2 6292
    mitochondrion organization 6.1087E-4 2 156 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    actin binding 1.0611E-5 2 21 2 6292
    ATP binding 1.3945E-5 2 24 2 6292
    adenyl ribonucleotide binding 1.5158E-5 2 25 2 6292
    adenyl nucleotide binding 2.1979E-5 2 30 2 6292
    purine nucleoside binding 2.3495E-5 2 31 2 6292
    nucleoside binding 2.5061E-5 2 32 2 6292
    ribonucleotide binding 4.1432E-5 2 41 2 6292
    purine ribonucleotide binding 4.1432E-5 2 41 2 6292
    purine nucleotide binding 6.6999E-5 2 52 2 6292
    structural constituent of cytoskeleton 6.9626E-5 2 53 2 6292
    nucleotide binding 8.6451E-5 2 59 2 6292
    cytoskeletal protein binding 8.6451E-5 2 59 2 6292
    structural molecule activity 2.8947E-3 2 339 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle