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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.59646224798]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SPA2
  • polarisome
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • mating projection tip
    		•
  • bipolar cellular bud site selection
  • regulation of initiation of mating projection growth
  • pseudohyphal growth
  • actin filament organization
  • regulation of termination of mating projection growth
  • Rho protein signal transduction
    		•
  • cytoskeletal regulatory protein binding
    		•
    SPH1
  • polarisome
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • mating projection
    		•
  • bipolar cellular bud site selection
  • pseudohyphal growth
  • actin filament organization
  • Rho protein signal transduction
    		•
  • cytoskeletal regulatory protein binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    polarisome 7.579E-7 2 6 2 6292
    incipient cellular bud site 5.0022E-5 2 45 2 6292
    cell projection 5.9419E-5 2 49 2 6292
    mating projection 5.9419E-5 2 49 2 6292
    cellular bud tip 8.0641E-5 2 57 2 6292
    cell cortex part 2.304E-4 2 96 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    cellular bud neck 4.1715E-4 2 129 2 6292
    cellular bud 6.9196E-4 2 166 2 6292
    site of polarized growth 7.0879E-4 2 168 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Rho protein signal transduction 9.6001E-6 2 20 2 6292
    bipolar cellular bud site selection 2.8346E-5 2 34 2 6292
    Ras protein signal transduction 4.1432E-5 2 41 2 6292
    small GTPase mediated signal transduction 1.0186E-4 2 64 2 6292
    actin filament organization 1.151E-4 2 68 2 6292
    pseudohyphal growth 1.151E-4 2 68 2 6292
    cytokinesis, site selection 1.3647E-4 2 74 2 6292
    cellular bud site selection 1.3647E-4 2 74 2 6292
    cell cycle cytokinesis 1.5966E-4 2 80 2 6292
    cell growth 1.7194E-4 2 83 2 6292
    establishment of cell polarity 1.7614E-4 2 84 2 6292
    establishment or maintenance of cell polarity 1.8038E-4 2 85 2 6292
    asexual reproduction 2.0236E-4 2 90 2 6292
    cell budding 2.0236E-4 2 90 2 6292
    filamentous growth of a population of unicellular organisms 2.0236E-4 2 90 2 6292
    growth of unicellular organism as a thread of attached cells 2.0236E-4 2 90 2 6292
    cytokinetic process 2.1151E-4 2 92 2 6292
    filamentous growth 2.8118E-4 2 106 2 6292
    regulation of cell size 3.0847E-4 2 111 2 6292
    cytokinesis 3.1407E-4 2 112 2 6292
    actin cytoskeleton organization 3.1973E-4 2 113 2 6292
    regulation of anatomical structure size 3.2544E-4 2 114 2 6292
    regulation of cellular component size 3.2544E-4 2 114 2 6292
    intracellular signal transduction 3.312E-4 2 115 2 6292
    actin filament-based process 3.4287E-4 2 117 2 6292
    cell morphogenesis 3.9158E-4 2 125 2 6292
    cellular component morphogenesis 4.7763E-4 2 138 2 6292
    intracellular signaling pathway 5.2022E-4 2 144 2 6292
    growth 5.275E-4 2 145 2 6292
    cell division 5.275E-4 2 145 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    reproduction of a single-celled organism 1.1841E-3 2 217 2 6292
    regulation of initiation of mating projection growth 1.2712E-3 2 4 1 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    signaling 1.598E-3 2 252 2 6292
    anatomical structure morphogenesis 1.6621E-3 2 257 2 6292
    anatomical structure development 1.7012E-3 2 260 2 6292
    regulation of termination of mating projection growth 1.9064E-3 2 6 1 6292
    cellular developmental process 1.9175E-3 2 276 2 6292
    regulation of cell projection organization 2.224E-3 2 7 1 6292
    regulation of mating projection assembly 2.224E-3 2 7 1 6292
    regulation of cell projection assembly 2.224E-3 2 7 1 6292
    reproduction 2.7096E-3 2 328 2 6292
    developmental process 2.7595E-3 2 331 2 6292
    regulation of cell morphogenesis 2.859E-3 2 9 1 6292
    mating projection assembly 3.1764E-3 2 10 1 6292
    regulation of response to stimulus 3.1764E-3 2 10 1 6292
    cell projection assembly 3.4937E-3 2 11 1 6292
    cell projection organization 3.4937E-3 2 11 1 6292
    regulation of anatomical structure morphogenesis 3.4937E-3 2 11 1 6292
    regulation of developmental process 3.4937E-3 2 11 1 6292
    regulation of cellular component biogenesis 5.7138E-3 2 18 1 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    cell morphogenesis involved in conjugation with cellular fusion 6.9813E-3 2 22 1 6292
    cell morphogenesis involved in conjugation 7.6148E-3 2 24 1 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cytoskeletal regulatory protein binding 7.579E-7 2 6 2 6292
    cytoskeletal protein binding 8.6451E-5 2 59 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle