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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.61997719071]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SPC110
  • inner plaque of spindle pole body
  • central plaque of spindle pole body
    		•
  • microtubule nucleation
    		•
  • structural constituent of cytoskeleton
    		•
    TUB4
  • inner plaque of spindle pole body
  • gamma-tubulin small complex, spindle pole body
  • outer plaque of spindle pole body
    		•
  • microtubule nucleation
  • mitotic spindle organization in nucleus
    		•
  • structural constituent of cytoskeleton
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    inner plaque of spindle pole body 3.0316E-7 2 4 2 6292
    microtubule organizing center part 6.0632E-6 2 16 2 6292
    microtubule organizing center 9.8679E-5 2 63 2 6292
    spindle pole body 9.8679E-5 2 63 2 6292
    spindle pole 1.151E-4 2 68 2 6292
    spindle 1.9786E-4 2 89 2 6292
    microtubule cytoskeleton 2.8118E-4 2 106 2 6292
    gamma-tubulin complex 9.5344E-4 2 3 1 6292
    gamma-tubulin small complex, spindle pole body 9.5344E-4 2 3 1 6292
    gamma-tubulin small complex 9.5344E-4 2 3 1 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292
    central plaque of spindle pole body 1.5888E-3 2 5 1 6292
    outer plaque of spindle pole body 1.9064E-3 2 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    microtubule nucleation 1.2783E-5 2 23 2 6292
    microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
    microtubule-based process 3.0847E-4 2 111 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    mitotic spindle organization in nucleus 8.248E-3 2 26 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    structural constituent of cytoskeleton 6.9626E-5 2 53 2 6292
    structural molecule activity 2.8947E-3 2 339 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle