From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Sui2. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 5 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
eukaryotic translation initiation factor 2 complex | 2.4099E-10 | 5 | 3 | 3 | 6292 |
multi-eIF complex | 1.3479E-8 | 5 | 8 | 3 | 6292 |
eukaryotic translation initiation factor 2B complex | 5.0479E-6 | 5 | 5 | 2 | 6292 |
guanyl-nucleotide exchange factor complex | 1.0594E-5 | 5 | 7 | 2 | 6292 |
protein complex | 1.913E-4 | 5 | 1137 | 5 | 6292 |
ribosome | 9.043E-4 | 5 | 290 | 3 | 6292 |
macromolecular complex | 1.1794E-3 | 5 | 1635 | 5 | 6292 |
ribonucleoprotein complex | 4.783E-3 | 5 | 514 | 3 | 6292 |
cytoplasmic part | 9.5281E-3 | 5 | 2482 | 5 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
translational initiation | 1.0368E-11 | 5 | 42 | 5 | 6292 |
translation | 7.4317E-7 | 5 | 376 | 5 | 6292 |
regulation of translational initiation | 2.771E-5 | 5 | 11 | 2 | 6292 |
cellular protein metabolic process | 1.4379E-4 | 5 | 1074 | 5 | 6292 |
protein metabolic process | 1.9046E-4 | 5 | 1136 | 5 | 6292 |
cellular macromolecule biosynthetic process | 2.3732E-4 | 5 | 1187 | 5 | 6292 |
macromolecule biosynthetic process | 2.3933E-4 | 5 | 1189 | 5 | 6292 |
gene expression | 3.5034E-4 | 5 | 1283 | 5 | 6292 |
regulation of translation | 7.924E-4 | 5 | 57 | 2 | 6292 |
posttranscriptional regulation of gene expression | 9.0741E-4 | 5 | 61 | 2 | 6292 |
cellular biosynthetic process | 9.5349E-4 | 5 | 1567 | 5 | 6292 |
biosynthetic process | 1.065E-3 | 5 | 1602 | 5 | 6292 |
regulation of cellular protein metabolic process | 1.127E-3 | 5 | 68 | 2 | 6292 |
regulation of protein metabolic process | 1.3337E-3 | 5 | 74 | 2 | 6292 |
cellular macromolecule metabolic process | 6.2991E-3 | 5 | 2285 | 5 | 6292 |
macromolecule metabolic process | 7.2329E-3 | 5 | 2349 | 5 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
translation initiation factor activity | 9.8393E-13 | 5 | 27 | 5 | 6292 |
translation factor activity, nucleic acid binding | 1.3236E-11 | 5 | 44 | 5 | 6292 |
nucleic acid binding | 1.3109E-5 | 5 | 666 | 5 | 6292 |
guanyl-nucleotide exchange factor activity | 3.5115E-4 | 5 | 38 | 2 | 6292 |
binding | 3.6564E-4 | 5 | 1294 | 5 | 6292 |
GTPase regulator activity | 1.7159E-3 | 5 | 84 | 2 | 6292 |
nucleoside-triphosphatase regulator activity | 2.19E-3 | 5 | 95 | 2 | 6292 |