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Protein Overview: HMS1

General Information:
Name(s) found: HMS1 / YOR032C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Basic helix-loop-helix (bHLH) protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 434 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: pseudohyphal growth [IGILink to PubMed article]
    Molecular Function: transcription factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNFQKPFSG SSDGNSVMND LGNKVAIKVF DCRSAQDGSE EQNVNVTTNQ MYLMFQSNNY  60
   61 NVPPPNYNTE DLGSQGPPTH AYYAPFQHPI HLQPPVPPVY KNNTYSATDQ YSDSSFPNTS 120
  121 GHTPVIDSNY YNDALASIPT TTTGSTTMTT DNGNTIDSEE YIDNMEVFSS EENENIDNVK 180
  181 QTDLKSEKDS SLLSAASIVK KEQLSGFENF LPLSKTESPL VTADEIKSSL NLENIDNADS 240
  241 MSFKLKTSPI RKHFHVKPKR ITRVRTGRVS HNIIEKKYRS NINDKIEQLR RTVPTLRVAY 300
  301 KKCNDLPITS RDLADLDGLE PATKLNKASI LTKSIEYICH LERKCLQLSL ANQHLSNDTR 360
  361 DSFVHLTEPS QPLSDNSSSE QVQKQTRSCQ RQRQRQPRQQ QPLHNIQYNI PHQNGLMSGT 420
  421 NNSHDMDFNN AGDF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADK1 ATP3 ATP5 ATP7 CDC14 DPM1 FUR1 GLC7 HEF3 HMS1 MCR1 SNF4 SPE3 SSZ1 TPS1 TSA2 VAS1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CIA1 HMS1 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..263] MSA 9.265997 View MSA. No confident structure predictions are available.
    2 View Details [264..434] PSI-BLAST 45.69897 SREBP-1a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.71844613492852 bayes_pls_golite062009
  • DNA binding
    		•  1.86563747084791 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.821185547269 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.7383733164042 bayes_pls_golite062009
  • transcription factor activity
    		•  1.60036420700371 bayes_pls_golite062009
  • protein binding
    		•  1.2438981435533 bayes_pls_golite062009
  • transcription factor binding
    		•  0.181447848144379 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle