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Protein Overview: RTG1

General Information:
Name(s) found: RTG1 / YOL067C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 177 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: protein localization [IGILink to PubMed article][IMPLink to PubMed article]
    mitochondria-nucleus signaling pathway [IDALink to PubMed article][IMPLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [IDALink to PubMed article]
    Molecular Function: transcription coactivator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSIPAGTDP GSCGANFKND RKRRDKINDR IQELLSIIPK DFFRDYYGNS GSNDTLSEST  60
   61 PGALGLSSKA KGTGTKDGKP NKGQILTQAV EYISHLQNQV DTQNREEVEL MVKATQLAKQ 120
  121 TGTIVNDINL ENTSAEVALS RIGVGPLAAT NDDSVRPPAK RLSSFEYGGY GEYGNGS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) RTG1 RTG3
    View Details (MIPS) Mewes HW, et al. (2004) RTG1 RTG3
    View Details Krogan NJ, et al. (2006) RTG1 RTG3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RTG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] ORFEUS 7.44 SREBP-1a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.08855036296174 bayes_pls_golite062009
  • DNA binding
    		•  4.62750596333801 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.3580974006648 bayes_pls_golite062009
  • transcription factor activity
    		•  4.22667982381176 bayes_pls_golite062009
  • binding
    		•  3.63719401349018 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.11931609869373 bayes_pls_golite062009
  • transcription factor binding
    		•  2.33137487648005 bayes_pls_golite062009
  • transcription activator activity
    		•  2.29259809049377 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.9803796973294 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  1.81708512383143 bayes_pls_golite062009
  • protein binding
    		•  1.48748521104247 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.30186253699056 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.828519845330998 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.431241241672784 bayes_pls_golite062009
  • promoter binding
    		•  0.359574623760154 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.172100901723138 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle