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View Structure Prediction Details

Protein: RTG1
Organism: Saccharomyces cerevisiae
Length: 177 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RTG1.

Description E-value Query
Range
Subject
Range
RTG1 - Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisom...
RTG1_YEAST - Retrograde regulation protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTG1 PE=...
6.0E-94 [1..165] [1..165]

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Predicted Domain #1
Region A:
Residues: [1-177]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSIPAGTDP GSCGANFKND RKRRDKINDR IQELLSIIPK DFFRDYYGNS GSNDTLSEST  60
   61 PGALGLSSKA KGTGTKDGKP NKGQILTQAV EYISHLQNQV DTQNREEVEL MVKATQLAKQ 120
  121 TGTIVNDINL ENTSAEVALS RIGVGPLAAT NDDSVRPPAK RLSSFEYGGY GEYGNGS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.44
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.08855036296174 bayes_pls_golite062009
DNA binding 4.62750596333801 bayes_pls_golite062009
nucleic acid binding 4.3580974006648 bayes_pls_golite062009
transcription factor activity 4.22667982381176 bayes_pls_golite062009
binding 3.63719401349018 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.11931609869373 bayes_pls_golite062009
transcription factor binding 2.33137487648005 bayes_pls_golite062009
transcription activator activity 2.29259809049377 bayes_pls_golite062009
sequence-specific DNA binding 1.9803796973294 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 1.81708512383143 bayes_pls_golite062009
protein binding 1.48748521104247 bayes_pls_golite062009
transcription cofactor activity 1.30186253699056 bayes_pls_golite062009
transcription repressor activity 0.828519845330998 bayes_pls_golite062009
transcription corepressor activity 0.431241241672784 bayes_pls_golite062009
promoter binding 0.359574623760154 bayes_pls_golite062009
transcription coactivator activity 0.172100901723138 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle