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Protein Overview: PFA4

General Information:
Name(s) found: PFA4 / YOL003C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 378 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: protein amino acid palmitoylation [IMPLink to PubMed articleLink to PubMed article][ISSLink to PubMed articleLink to PubMed article]
    Molecular Function: protein-cysteine S-palmitoleyltransferase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVKLRWPWL GIAIPTFLIS FIGYGAHYFI LSNFLSVPKQ ITFEFCLSMI WLSYYLAICT  60
   61 NPGRPLPNYK PPPDIWRNFC KKCQSYKPER SHHCKTCNQC VLMMDHHCPW TMNCVGFANY 120
  121 PHFLRFLFWI IVTTSVLFCI QAKRIYFIWQ QRHLPGYFFK KSELIFLTIS SPLNSFVLLT 180
  181 ITILFLRCLF NQILNGRSQI ESWDMDRLES LFNSGRLTQK LIDNTWRIYP ESRSFQNKKD 240
  241 AEEHLTKKRP RFDELVNFPY DFDLYTNALL YLGPIHLWLW PYGVPTGDGN NFPKNGISKY 300
  301 EANSSLEDHI LSLPWPPDGG KTNTVFNHGS STIEMRNESG EQLIRTRLPQ NGRHASREKW 360
  361 YNDWGESLDD FGVDVDME

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YIF1 PFA4 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] Pfam 38.408935 DHHC zinc finger domain No confident structure predictions are available.
    2 View Details [155..378] deduced N/A No confident structure predictions are available.
    3 View Details [258..292] MSA 1.187995 View MSA. No confident structure predictions are available.
    4 View Details [293..378] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.481338897251745 bayes_pls_golite062009
  • binding
    		•  0.0373927717713547 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle