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Protein Overview: ARA2

General Information:
Name(s) found: ARA2 / YMR041C [SGD]
Description(s) found:
Found 31 descriptions.
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  • NAD-dependent arabinose dehydrogenase, involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 335 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: L-ascorbic acid biosynthetic process [IMPLink to PubMed article]
    Molecular Function: D-arabinose 1-dehydrogenase [NAD(P)+] activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNEKVNPFD LASVSPLVLG GAILNQQYTD EPESIPLEDI IKYAFSHGIN AIDTSPYYGP  60
   61 SEVLYGRALS NLRNEFPRDT YFICTKVGRI GAEEFNYSRD FVRFSVHRSC ERLHTTYLDL 120
  121 VYLHDVEFVK FPDILEALKE LRTLKNKGVI KNFGISGYPI DFITWLAEYC STEESDIGSL 180
  181 DAVLSYCNLN LQNNKLLNFR ERLLRNAKLK MVCNASILSM SLLRSQETRQ FHPCSHELRE 240
  241 CASQAAKYCQ EQNVDLADLA TRYAISEWVG KGPVVLGVSS MEELKLALDN YEIVKSNGNR 300
  301 LSSKDGQLVE YIQKNIFKEH FNEEWSSGIP HPEMI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARA2 AYT1 BRO1 CDC73 CTR9 GLO4 HHT1, HHT2 LEO1 PAF1 PML39 POB3 PSH1 RTF1 SEN1 SPT16 YHR035W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222]
    [254..302]    		 PSI-BLAST 104.703922 Voltage-dependent K+ channel beta subunit
    2 View Details [223..253]
    [303..335]    		 PSI-BLAST 104.703922 Voltage-dependent K+ channel beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • potassium channel activity
    		•  7.51963276589303 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  7.40239094355354 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  6.67507110634301 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  6.588881463055 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.52286930358188 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.50716590143831 bayes_pls_golite062009
  • cation channel activity
    		•  5.72172645555113 bayes_pls_golite062009
  • ion channel activity
    		•  5.15119282480682 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  5.07214658557001 bayes_pls_golite062009
  • channel activity
    		•  5.07214658557001 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  5.02503292701043 bayes_pls_golite062009
  • gated channel activity
    		•  4.92848832197692 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.63772951680109 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.58068601897668 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.46488926936937 bayes_pls_golite062009
  • catalytic activity
    		•  1.68179794468736 bayes_pls_golite062009
  • transporter activity
    		•  1.24767072239634 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.03420335553507 bayes_pls_golite062009
  • potassium channel regulator activity
    		•  1.03017249802223 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.783004917746429 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.538083956961548 bayes_pls_golite062009
  • binding
    		•  0.214346441566082 bayes_pls_golite062009
    		• 0.139676323362391 bayes_pls_golite062009
  • channel regulator activity
    		•  0.12154513851913 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.0465377885825481 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.0143508436041874 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle