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Protein Overview: TOM20

General Information:
Name(s) found: TOM20 / YGR082W [SGD]
Description(s) found:
Found 37 descriptions.
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  • Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 183 amino acids

    Gene Ontology:
    Cellular Component: integral to mitochondrial outer membrane [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    mitochondrial outer membrane translocase complex [TASLink to PubMed article]
    Biological Process: protein import into mitochondrial matrix [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: protein transporter activity [IPILink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQSNPILRG LAITTAIAAL SATGYAIYFD YQRRNSPQFR KVLRQRAKEQ AKMEEQAKTH  60
   61 AKEVKLQKVT EFLSMELAKD PIPSDPSERE ATFTTNVENG ERLSMQQGKE LEAASKFYKA 120
  121 LTVYPQPADL LGIYQRSIPE AIYEYIILMI AILPPANVAS FVKGVVGSKA ESDAVAEAND 180
  181 IDD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) SAM37 TOM20 TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOM71
    View Details Qiu et al. (2008) PAM16 SSC1 TIM17 TIM23 TIM44 TOM20 TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOM71

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TOM20 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] Pfam 8.823909 MAS20 protein import receptor Confident ab initio structure predictions are available.
    2 View Details [75..183] PSI-BLAST 17.522879 Mitochondrial import receptor subunit Tom20

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  3.40898729129243 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  3.40898729129243 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.85488085984023 bayes_pls_golite062009
  • protein transporter activity
    		•  2.05250883327513 bayes_pls_golite062009
  • transporter activity
    		•  1.79559401386194 bayes_pls_golite062009
  • binding
    		•  1.66795187393523 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.6303525042646 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49267876312697 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.3436996680931 bayes_pls_golite062009
  • protein binding
    		•  1.10534436186662 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.0671316259706 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.06141451496527 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.01882616059722 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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