Protein Overview: IC1_RAT

General Information:
Name(s) found:	IC1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81892278\|sp\|Q6P734.1\|IC1_RAT RecName: Full=Plasma protease C1 inhibitor; Short=C1 Inh; Short=C1Inh; AltName: Full=C1 esterase inhibitor; AltName: Full=C1-inhibiting factor; Flags: Precursor [NCBI NR] gi\|40018558\|ref\|NP_954524.1\| serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) [Rattus norvegicus] [NCBI NR] gi\|38197406\|gb\|AAH61860.1\| Serine (or cysteine) peptidase inhibitor, clade G, member 1 [Rattus norvegicus] [NCBI NR] gi\|149022421\|gb\|EDL79315.1\| serine (or cysteine) peptidase inhibitor, clade G, member 1 [Rattus norvegicus] [NCBI NR] Plasma protease C1 inhibitor OS=Rattus norvegicus GN=Serping1 PE=2 SV=1 [Swiss-Prot] serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) [HMR_022704-rand.fasta] serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) [Rattus norvegicus]gi\|38197406\|gb\|AAH61860.1\| Serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) [Rat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Serine [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serine (or cysteine) peptidase inhibitor, clade G, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Serine (or cysteine) peptidase inhibitor, clade G, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SERINE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Serping1 Plasma protease C1 inhibitor [rat-ipi-250309-contam.fasta] plasma protease C1 inhibitor precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Plasma protease C1 inhibitor OS=Rattus norvegicus GN=Serping1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	504 amino acids
Gene Ontology:
Cellular Component:	platelet alpha granule lumen [UNKNOWN] extracellular space [UNKNOWN][IEA] extracellular region [UNKNOWN][IEA] cellular_component [ND]
Biological Process:	biological_process [ND] complement activation, classical pathway [IEA] innate immune response [IEA] negative regulation of complement activation, lectin pathway [UNKNOWN][ISS] blood coagulation [IEA]
Molecular Function:	peptidase inhibitor activity [IEA] serine-type endopeptidase inhibitor activity [UNKNOWN][ISS] protein binding [UNKNOWN] complement binding [UNKNOWN][IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKLTPLTL LLLLLAGDRA FSDSEVTSHS SQDPLVVQEG SRDSVPERDG SRSPIEHTGQ  60
   61 SSTWPTTSGS TKISNDTMDQ VANESFIQHV QPAAQLPEDS PSQSPVNSSS PPSTASAPPT 120
  121 QAPTEPLCPE PLAWCSDSDR DSSEATLSEA LTDFSVKLYH AFSATKKAET NMAFSPFSIA 180
  181 SLLTQVLLGA GDSTKSNLED ILSYPKDFAC VHQTLKAFSS KGVTSVSQIF HSPDLAIRDT 240
  241 YVNASLSLYG SSPRVLGPDG DANLKLINTW VAENTNHKIN ELLDSLPSDT RLVLLNAVYL 300
  301 SAKWKKTFEQ KKMMASFLYK NSMIKVPMLS SKKYPLALFN DQTLKAKVGQ LQLSHNLSFV 360
  361 IMVPQSPTHQ LEDMEKALNP TVFKAILKKL ELSKFQPTYV MMPRIKVKSS QDMLSIMEKL 420
  421 EFFDFTYDLN LCGLTEDPDL QVSSMKHETV LELTETGVEA AAASTISVAR NLLIFEVQQP 480
  481 FLFLLWDQRH KFPVFMGRVY DPRA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: IC1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: