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Protein Overview: FBpp0309007

General Information:
Name(s) found: FBpp0309007 [FlyBase]
Description(s) found:
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  • gi|45550429|ref|NP_610999.3| Pcf11 [Drosophila melanogaster] [NCBI NR]
  • gi|45445551|gb|AAF58192.3| Pcf11 [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=2R:complement(10748887..10749626,10749700..10750173,10750236..10752563,10752677..10752779,10752847..10752952,10753013..10753556,10754989..10755676,10755738..10756067,10756133..10756348,10756412..10756537,10757554..10757736); ID=FBpp0309007; name=Inr-a-PG; parent=FBgn0264962,FBtr0339986; dbxref=FlyBase:FBpp0309007,FlyBase_Annotation_IDs:CG10228-PG; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r5.56; species=Dmel; [FlyBase]
  • (AAF58192) CG10228-PA [DrosMelano7227.FASTAC.txt]
  • (AE003813) CG10228 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10228-PA [Drosophila melanogaster]gi|45550429|ref|NP_610999.3| CG10228-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(10748887..10749626,10749700..10750173,10750236..10752563,10752677..10752779,10752847..10752952,10753013..10753556,10754989..10755676,10755738..10756067,10756133..10756348,10756412..10756537,10757554..10757736); ID=FBpp00865 [fly-100309-contam.fasta]
  • CG10228-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Pcf11 CG10228-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(10748887..10749626,10749700..10750173,10750236..10752563,10752677..10752779,10752847..10752952,10753013..10753556,10754989..10755676,10755738..10756067,10756133..10756348,10756412..10756537,10757554..10757736); ID=FBpp0086588; name=Pcf11-PA; parent=FBgn0022063,FBtr0087458; dbxref=GB_protein:AAF58192.2,FlyBase:FBpp0086588,FlyBase_Annotation_IDs:CG10228-PA,GB_protein:AAF58192.3,REFSEQ:NP_610999,GB_protein:AAF58192; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(10748887..10749626,10749700..10750173,10750236..10752563,10752677..10752779,10752847..10752952,10753013..10753556,10754989..10755676,10755738..10756067,10756133..10756348,10756412..10756537,10757554..10757736); ID=FBpp0086588; name=Pcf11-PA; parent=FBgn0022063,FBtr0087458; dbxref=GB_protein:AAF58192.2,FlyBase:FBpp0086588,FlyBase_Annotation_IDs:CG10228-PA,GB_protein:AAF58192.3,REFSEQ:NP_610999,GB_protein:AAF58192; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2R:complement(join(14870049..14870231,14868907..14869032,14868628..14868843,14868233..14868562,14867484..14868171,14865508..14866051,14865342..14865447,14865172..14865274,14862731..14865058,14862195..14862668,14861382..14862121)); ID=FBpp0309007; name=Inr-a-PG; parent=FBgn0264962,FBtr0339986; dbxref=FlyBase:FBpp0309007,FlyBase_Annotation_IDs:CG10228-PG,GB_protein:AHN56227,REFSEQ:NP_001286429; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(14870049..14870231,14868907..14869032,14868628..14868843,14868233..14868562,14867484..14868171,14865508..14866051,14865342..14865447,14865172..14865274,14862731..14865058,14862195..14862668,14861382..14862121)); ID=FBpp0309007; name=Pcf11-PG; parent=FBgn0264962,FBtr0339986; dbxref=FlyBase:FBpp0309007,FlyBase_Annotation_IDs:CG10228-PG,GB_protein:AHN56227,REFSEQ:NP_001286429; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A1Z9W4, Inverse regulator a, isoform G OS=Drosophila melanogaster GN=Pcf11 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0309007 type=protein; loc=2R:complement(join(14870049..14870231,14868907..14869032,14868628..14868843,14868233..14868562,14867484..14868171,14865508..14866051,14865342..14865447,14865172..14865274,14862731..14865058,14862195..14862668,14861382..14862121)); ID=FBpp0309007; name=Pcf11-PG; parent=FBgn0264962,FBtr0339986; dbxref=FlyBase:FBpp0309007,FlyBase_Annotation_IDs:CG10228-PG,GB_protein:AHN56227,REFSEQ:NP_001286429; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(14870049..14870231,14868907..14869032,14868628..14868843,14868233..14868562,14867484..14868171,14865508..14866051,14865342..14865447,14865172..14865274,14862731..14865058,14862195..14862668,14861382..14862121)); ID=FBpp0309007; name=Pcf11-PG; parent=FBgn0264962,FBtr0339986; dbxref=FlyBase:FBpp0309007,FlyBase_Annotation_IDs:CG10228-PG,GB_protein:AHN56227,REFSEQ:NP_001286429,UniProt/TrEMBL:A0A0B4LFE6; MD5=4d700c2adff40821003bb6be91984d19; length=1945; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1945 amino acids

    Gene Ontology:
    Cellular Component: mRNA cleavage factor complex [ISS]
    Biological Process: mRNA cleavage [ISS]
    Molecular Function: RNA binding [IDA]
    negative transcription elongation factor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQLFQNYRD DERRIGEEYL SSLQDLNCNS KPLINMLTML AEENINYAHI IVKVVEYYIS  60
   61 QVAPEFKLPI LYLIDSIVKN VKSSYVQLFG QCIVNIFLHA FESVQHSQSQ VLEKVRERMY 120
  121 ALRQTWNEVF PPSKMYALDV KVKRLDNNWP ITAKQPTNKI HVNPAIHVNP DFLKPGLVPG 180
  181 MPGNPTITSD MEEILQAKTR ELLELKKRKL ELELEQTKKH LEEQERQLTQ TTDAMVGAPI 240
  241 IMPAPTPAAI CPPITDPGIA VHNQRAPGVM GNVGPVMHNM PVAPQLFANK PKVHPVNPAL 300
  301 LNSVRQRDPR LARQMHAASS HPAAPARNDP RLEAKSSSSQ KSSRSRSKSP VRNSSSRSGK 360
  361 SGSSSHSSSS SRKRSESKSS TTSSSSSSSD VRHKGVTASS SNQPTVKRSG KITSKDSDRY 420
  421 VRNGSPLGSA KRKSSSPSSS PSKSKRSTSH KSSSSRGKTS SLRSRSRSPV FMDVDLRTGV 480
  481 RSKSPESRAV APSSLPLAGA SLPASAKAPK DLEKRHPPAP PSPPIIDVSS MDIDLRRPKT 540
  541 PPPPTFDSVD SLDQKDTTSG HISSTIIQAS GASNASPSGA STSKLPAKVS FKIQKQFNKL 600
  601 EKSTANLSTV SMLNSNPTTS GTPAASLVRQ SSPSPSSSSI SSQGNVSDAL QLSINKLLQV 660
  661 QGGAGEKRPA DALPPHIDGE EQPPQQKRSK SAKLDALFGS EDVDLRREIL VVKPGVIVVE 720
  721 DDSMDECDVD KPTKKSGSPP KKATLEELRA KLANSARIQN KQGKSDKSRD QAVSQRLKQL 780
  781 AELKVNDDSQ EAHDEKVRTI LSQAQEMYEN NGMNQEQYKD LVQKVVAINE NSKIKESRRR 840
  841 DNDLERNAAR DAVLRKRIPK LKGNENHSAG SPHTDGSPRY DDQPAAAPEK PSNKRDKTKR 900
  901 EMKRRKPTKW GEQVDAGAAQ RTAWQLANVN NNNNNNNNKR GGIQLPVQPQ AGFRGMPWQQ 960
  961 PPAMVLGQSA VPPPPQPPSM ISMPPVPPVT MTKAINSLDN PMADVVRSIT IDGGSKEIRF1020
 1021 YNQVAIIFMD GDQPHEIGFQ PGQRVIFIDH NEPLPLCFND DYKPFHLDGQ LHRIRFGFPS1080
 1081 RELYIDEHWY EIYFGGPAVS VPIGNKLHII KAEGPPPNVD IGRVRRDLVV GKINMIADAH1140
 1141 TIVPLFLDAR QQTFQLGAEQ HSLQFVDSFQ YALLDGQLQK MEYGGLPKGM MLNGGRSCFI1200
 1201 RFGTLPKGVI AGKTHVADMV YIKTDAPAEP PKPPPIIVKP PPVVEQPKPA PVAVAPISLP1260
 1261 AAAAALESLN INDLFQKLVS SGIIGGATAA PTLPAADSSA AKEPTASATE PSTASATVAP1320
 1321 ATLPAGPPAE PIKRIDLRKP ESIKTRQAAV VAVLYLGMQC SSCGVRFPPE QTIKYSQHLD1380
 1381 WHFRQNRRER DSTRKATSRK WYYDLNDWRQ YEEIEDVEER EKNFLEAQGQ PGGVEALDEL1440
 1441 SQQRSLDSPV PTCAAGRDDV DHCCDMCHEK FEQFYNEELE EWHLRSAIRV EDKIYHPLCY1500
 1501 EDYKASLNPP TEVKSDQDVD MNNTDDNAMD TLIKVEDDED EGTPNSSQPI FEDDDDDVIV1560
 1561 LPNEEPSVTE IVDDDDEDEY VPGNVTRADM GNESQDKTES NSETKEPKKD QVELGEQQQN1620
 1621 ESANESDVEI QEPNIPFTDL DTYVEKEMDE ATRAALLNVK IKEEPKDEYE EDEDDGFEDV1680
 1681 GTVVSLLPLP EDEISIHSSE TQTHTIGSSA SPATIERPAS VTSLSLPANE ADELEQGDAN1740
 1741 TDTDAELNGE KQEATHNLSA VGPALPLASI VNKIKINITK NTSSNSHNSA SNTTTTDSQV1800
 1801 SAISVIGGSG AAGGASGAGD PVQQVNAIQT ISTIPVLCGG NTFVPKIATS TPSNVISSIS1860
 1861 VIGSTYGASS SSNGSRSTTS TASSAPAASL LAETGSLKSP TPPLATVDPD PEPVVEQKPA1920
 1921 LRNATLKRTK KVQNGIETSG LCSIM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] PSI-BLAST 32.522879 The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model
    2 View Details [149..357] deduced N/A No confident structure predictions are available.
    3 View Details [358..421] deduced N/A No confident structure predictions are available.
    4 View Details [422..486] deduced N/A No confident structure predictions are available.
    5 View Details [487..685] deduced N/A No confident structure predictions are available.
    6 View Details [686..934] deduced N/A No confident structure predictions are available.
    7 View Details [935..1030] deduced N/A No confident structure predictions are available.
    8 View Details [1031..1217] deduced N/A No confident structure predictions are available.
    9 View Details [1218..1393] MSA 1.016991 View MSA. No confident structure predictions are available.
    10 View Details [1394..1511] deduced N/A No confident structure predictions are available.
    11 View Details [1512..1666] deduced N/A No confident structure predictions are available.
    12 View Details [1667..1817] MSA 2.080996 View MSA. No confident structure predictions are available.
    13 View Details [1818..1945] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.32938736470587 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.23669539775752 bayes_pls_golite062009
  • protein binding
    		•  1.06982968862424 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.0577402512508 bayes_pls_golite062009
  • DNA binding
    		•  0.977216329931465 bayes_pls_golite062009
  • transcription factor activity
    		•  0.41747784195632 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.
    12 No functions predicted.
    13 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle