Protein Overview: TRER_ECOLI

General Information:
Name(s) found:	TRER_ECOLI [Swiss-Prot]
Description(s) found: Found 11 descriptions. SHOW ALL	HTH-type transcriptional regulator treR (Trehalose operon repressor) - Escherichia coli [Swiss-Prot]
Organism:	Escherichia coli
Length:	315 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNRLTIKDI ARLSGVGKST VSRVLNNESG VSQLTRERVE AVMNQHGFSP SRSARAMRGQ  60
   61 SDKVVAIIVT RLDSLSENLA VQTMLPAFYE QGYDPIMMES QFSPQLVAEH LGVLKRRNID 120
  121 GVVLFGFTGI TEEMLAHWQS SLVLLARDAK GFASVCYDDE GAIKILMQRL YDQGHRNISY 180
  181 LGVPHSDVTT GKRRHEAYLA FCKAHKLHPV AALPGLAMKQ GYENVAKVIT PETTALLCAT 240
  241 DTLALGASKY LQEQRIDTLQ LASVGNTPLM KFLHPEIVTV DPGYAEAGRQ AACQLIAQVT 300
  301 GRSEPQQIII PATLS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..62]	PSI-BLAST	16.154902	NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor that mimics the gal repressor
2	View Details	[63..315]	PSI-BLAST	39.0	Trehalose repressor, C-terminal domain

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
DNA binding	3.60509310049517	bayes_pls_golite062009
transcription regulator activity	3.48897156115814	bayes_pls_golite062009
nucleic acid binding	3.34114111237501	bayes_pls_golite062009
binding	2.84855827811506	bayes_pls_golite062009
transcription factor activity	2.15956406789231	bayes_pls_golite062009
catalytic activity	0.374904657353081	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.29966985317584	bayes_pls_golite062009
sequence-specific DNA binding	0.11459677079129	bayes_pls_golite062009
transcription repressor activity	0.0485771867742395	bayes_pls_golite062009

2

Term	Confidence	Notes
transcription regulator activity	3.03730517010624	bayes_pls_golite062009
DNA binding	2.13752511265098	bayes_pls_golite062009
transcription factor activity	2.10452652023643	bayes_pls_golite062009
nucleic acid binding	2.05471649974481	bayes_pls_golite062009
binding	1.58080550382179	bayes_pls_golite062009
signal transducer activity	0.11302624216037	bayes_pls_golite062009
molecular transducer activity	0.11302624216037	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle