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Protein Overview: hdc-PC

General Information:
Name(s) found: hdc-PC / FBpp0084985 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene headcase is referred to in FlyBase by the symbol Dmel\hdc (CG15532, FBgn0010113). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26103656..26187891. It has the cytological map location 99E4-99F1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 37 alleles are reported. The phenotypes of these alleles are annotated with: epidermis; leg; embryonic/larval trachea; antenna; central nervous system; haltere; somatic muscle; tracheal system; wing; head. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1080 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA][NAS][TAS]
    Biological Process: negative regulation of terminal cell fate specification, open tracheal system [TAS]
    cell differentiation [NAS]
    terminal branching, open tracheal system [NAS][TAS]
    branch fusion, open tracheal system [TAS]
    RNA interference [IMP]
    open tracheal system development [NAS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPRRNSNIS SSGNSTQQQH QQQLQQQHQT QQHQLLQFYA ENVNSSGVLM APMQGTGGVG  60
   61 GVGGGGMVHC CLPSGDCRKL DTLIHLNELS LADCIRVLCN NENCSAGQYM HRECFEWWEA 120
  121 SVLQALKANG RARSWSERQR LQHLWTKKGY ELVQKACSCK CGRGQLRKDL DWVPPSSQGV 180
  181 IYLNGSGNRP TLANGSLSED DDKKKAKKKR NRNNNNNNGG GGGGGAGVNG NTKTPLSNNN 240
  241 GNSYAGLTPN PNVGVIGSGL PHNNGNTASN GSSGNNGSSG VLQTSALATF SNILNTNNVL 300
  301 GLDLRARAGS LSSSGAGSGS TSPSDSQSSG EISVSPVQQL LPQQQQQQQQ SLLIQPLGPA 360
  361 FGSNLLQNGL GLSKNLLIAP QQQQQQQLQQ QQQQQNNLPA LANISNFKPL ASYEQQQLVQ 420
  421 QQKNKEVELY SDRVRSTSGC NGIFSRRLDF SSFNLLPKTR LNSYQVKIED EGNHGNDETR 480
  481 LFILSSLAQS QMSRVACILC EEPLLVFDRY PLVDGSFFLS PKQHSSGCIE VKYEGRTLYL 540
  541 TCVCMSCLDG TSSSRAINCR FCKEPWDGSS LVLGTMYAYD IFAAMPCCAE RFKCNNCFKM 600
  601 LMHPQQRLSF YSDYSHGVTC PYCNTQDTHF VKPLTFCYAK TTATRLPTLA XHEAPLESPV 660
  661 GTGATTTQVP NAQGSPTASG CSSNTIASKQ PPKQPLYNAA IDYSAPLQQQ INPDLIGAHP 720
  721 HAQQHQQQVR QQQQQQQQQQ PQQQQQQQQQ QTQQQQSQQQ QQQQQQQHQP VVSTFQRGNF 780
  781 PQQSHKTMNM MAMADVMSKY QQQQHQQQQQ QRQQQHNLQP QQQHATQKGL EGLLLTNTNT 840
  841 SNNNSSSSSS SSISNLIISH NSASNTGNKM QPTWGQSDAI SALWGCSSSS SGCSSGSGSQ 900
  901 PSLSPTASSN GNDGSKMMLW AAQSSPQNAA TLRDGFKELQ RQQPPQQQVP QQQPHAASPT 960
  961 ASLTSSSSSS NGWSASHYGK PNIWELPGST GQRTPASSHD IFTDLLCNLS ISQDNSSQQA1020
 1021 SSKADASDVS SNSSSSAGEL LEAANIWRFP EYASSQLYME EPTGGAAACM QLFNDYLNMN1080
 1081

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..278] deduced N/A No confident structure predictions are available.
    2 View Details [279..425] deduced N/A No confident structure predictions are available.
    3 View Details [426..510] deduced N/A No confident structure predictions are available.
    4 View Details [511..645] FFAS03 1.03 No description for 2dfyX was found.
    5 View Details [646..960] PSI-BLAST 18.39794 Heavy meromyosin subfragment
    6 View Details [961..1080] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle