YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that mediates the adoption of a specific fate by a cell. Any biological process, occurring at the level of a multicellular organism, pertinent to its function. Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Any process that restricts, stops or prevents a cell from adopting a specific cell fate. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Process by which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange. Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates. Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of terminal cell fate specification, open tracheal system
Acc: GO:0035155
Aspect: Biological Process
Desc: Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.
Synonyms:
  • inhibition of terminal cell fate specification
  • down regulation of terminal cell fate specification
  • down-regulation of terminal cell fate specification
  • negative regulation of terminal cell fate specification
  • downregulation of terminal cell fate specification
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035155 - negative regulation of terminal cell fate specification, open tracheal system (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle