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Protein Overview: DPIB_ECOLI

General Information:
Name(s) found: DPIB_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Sensor kinase dpiB (EC 2.7.13.3) (Sensor kinase citA) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 552 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQLNENKQF AFFQRLAFPL RIFLLILVFS IFVIAALAQY FTASFEDYLT LHVRDMAMNQ  60
   61 AKIIASNDSV ISAVKTRDYK RLATIANKLQ RDTDFDYVVI GDRHSIRLYH PNPEKIGYPM 120
  121 QFTKQGALEK GESYFITGKG SMGMAMRAKT PIFDDDGKVI GVVSIGYLVS KIDSWRAEFL 180
  181 LPMAGVFVVL LGILMLLSWF LAAHIRRQMM GMEPKQIARV VRQQEALFSS VYEGLIAVDP 240
  241 HGYITAINRN ARKMLGLSSP GRQWLGKPIV EVVRPADFFT EQIDEKRQDV VANFNGLSVI 300
  301 ANREAIRSGD DLLGAIISFR SKDEISTLNA QLTQIKQYVE SLRTLRHEHL NWMSTLNGLL 360
  361 QMKEYDRVLA MVQGESQAQQ QLIDSLREAF ADRQVAGLLF GKVQRARELG LKMIIVPGSQ 420
  421 LSQLPPGLDS TEFAAIVGNL LDNAFEASLR SDEGNKIVEL FLSDEGDDVV IEVADQGCGV 480
  481 PESLRDKIFE QGVSTRADEP GEHGIGLYLI ASYVTRCGGV ITLEDNDPCG TLFSIYIPKV 540
  541 KPNDSSINPI DR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] FFAS03 4.0 Sensor Kinase CitA binding domain
    2 View Details [199..324] PSI-BLAST 5.045757 Crystal structure of the R220A metBJFIXL HEME domain
    3 View Details [325..552] PSI-BLAST 41.0 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • two-component sensor activity
    		•  2.88093868237858 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.86151216540335 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.80671328721504 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.62873572477094 bayes_pls_golite062009
  • signal transducer activity
    		•  1.10204821596482 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.10204821596482 bayes_pls_golite062009
  • binding
    		•  0.704248066961418 bayes_pls_golite062009
  • protein kinase activity
    		•  0.510808146850279 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.399812011068743 bayes_pls_golite062009
  • kinase activity
    		•  0.223004824807113 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0995264574132551 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.13913685347546 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • DNA binding
    		•  0.73243452463464 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.5545839402512 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transcription factor activity
    		•  0.36759096137141 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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