Protein Overview: BIOF_ECOLI

General Information:
Name(s) found:	BIOF_ECOLI [Swiss-Prot]
Description(s) found: Found 12 descriptions. SHOW ALL	8-amino-7-oxononanoate synthase (EC 2.3.1.47) (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase) - Escherichia coli [Swiss-Prot]
Organism:	Escherichia coli
Length:	384 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWQEKINAA LDARRAADAL RRRYPVAQGA GRWLVADDRQ YLNFSSNDYL GLSHHPQIIR  60
   61 AWQQGAEQFG IGSGGSGHVS GYSVVHQALE EELAEWLGYS RALLFISGFA ANQAVIAAMM 120
  121 AKEDRIAADR LSHASLLEAA SLSPSQLRRF AHNDVTHLAR LLASPCPGQQ MVVTEGVFSM 180
  181 DGDSAPLAEI QQVTQQHNGW LMVDDAHGTG VIGEQGRGSC WLQKVKPELL VVTFGKGFGV 240
  241 SGAAVLCSST VADYLLQFAR HLIYSTSMPP AQAQALRASL AVIRSDEGDA RREKLAALIT 300
  301 RFRAGVQDLP FTLADSCSAI QPLIVGDNSR ALQLAEKLRQ QGCWVTAIRP PTVPAGTARL 360
  361 RLTLTAAHEM QDIDRLLEVL HGNG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..384]	PSI-BLAST	84.522879	PLP-dependent acyl-CoA synthase (8-amino-7-oxonanoate synthase, AONS)

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
catalytic activity	2.66922865456094	bayes_pls_golite062009
threonine aldolase activity	1.96256164426812	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.85532625717753	bayes_pls_golite062009
transaminase activity	1.83482013760414	bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity	1.8294165617831	bayes_pls_golite062009
8-amino-7-oxononanoate synthase activity	1.68758133244562	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	1.48194418319516	bayes_pls_golite062009
5-aminolevulinate synthase activity	1.44455472154869	bayes_pls_golite062009
carbon-sulfur lyase activity	1.19843805346966	bayes_pls_golite062009
transferase activity	0.93810038069762	bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups	0.83247653897701	bayes_pls_golite062009
N-succinyltransferase activity	0.73312481571279	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	0.520614909745139	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	0.520614909745139	bayes_pls_golite062009
cystathionine beta-lyase activity	0.31229842545297	bayes_pls_golite062009
glycine C-acetyltransferase activity	0.20784545328672	bayes_pls_golite062009
glutamate-1-semialdehyde 2,1-aminomutase activity	0.0464359482474901	bayes_pls_golite062009
lyase activity	0.0414385380659299	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.71

Source: Reynolds et al. (2008)

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