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Protein Overview: ATOC_ECOLI

General Information:
Name(s) found: ATOC_ECOLI [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Acetoacetate metabolism regulatory protein atoC (Ornithine/arginine decarboxylase inhibitor) (Ornithine decarboxylase antizyme) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 461 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAINRILIV DDEDNVRRML STAFALQGFE THCANNGRTA LHLFADIHPD VVLMDIRMPE  60
   61 MDGIKALKEM RSHETRTPVI LMTAYAEVET AVEALRCGAF DYVIKPFDLD ELNLIVQRAL 120
  121 QLQSMKKEIR HLHQALSTSW QWGHILTNSP AMMDICKDTA KIALSQASVL ISGESGTGKE 180
  181 LIARAIHYNS RRAKGPFIKV NCAALPESLL ESELFGHEKG AFTGAQTLRQ GLFERANEGT 240
  241 LLLDEIGEMP LVLQAKLLRI LQEREFERIG GHQTIKVDIR IIAATNRDLQ AMVKEGTFRE 300
  301 DLFYRLNVIH LILPPLRDRR EDISLLANHF LQKFSSENQR DIIDIDPMAM SLLTAWSWPG 360
  361 NIRELSNVIE RAVVMNSGPI IFSEDLPPQI RQPVCNAGEV KTAPVGERNL KEEIKRVEKR 420
  421 IIMEVLEQQE GNRTRTALML GISRRALMYK LQEYGIDPAD V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..391] PSI-BLAST 88.69897 Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state
    2 View Details [392..461] PSI-BLAST 84.154902 Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.95073642969863 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.91141407779641 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.9017593265179 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.90014393273511 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.82370030183942 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.79922369980544 bayes_pls_golite062009
  • transporter activity
    		•  1.55572428045529 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.52217781539459 bayes_pls_golite062009
  • ATPase activity
    		•  1.48474288797022 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45919623810582 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  1.4031990658196 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.38483976298883 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.37457738689583 bayes_pls_golite062009
  • catalytic activity
    		•  1.37148167194523 bayes_pls_golite062009
  • binding
    		•  1.30574971150356 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.24278046928678 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.2014318795788 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.19670408144267 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.17063957238561 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.16918853509059 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.16885789920943 bayes_pls_golite062009
  • hydrolase activity
    		•  1.09839981963412 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.900561861643259 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.530058973650498 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.5127850474754 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.51230334374838 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.50688037036449 bayes_pls_golite062009
  • protein binding
    		•  0.502813311049029 bayes_pls_golite062009
  • nucleotide binding
    		•  0.49473184426584 bayes_pls_golite062009
  • DNA binding
    		•  0.460315660888175 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  0.32754685224555 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  0.128277449580549 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.109938795198381 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.0838665746103899 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle