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Protein Overview: ADA_ECOLI

General Information:
Name(s) found: ADA_ECOLI [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Regulatory protein ada (Regulatory protein of adaptative response) [Contains: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (O-6-methylguanine-DNA alkyltransferase)] - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKATCLTDD QRWQSVLARD PNADGEFVFA VRTTGIFCRP SCRARHALRE NVSFYANASE  60
   61 ALAAGFRPCK RCQPEKANAQ QHRLDKITHA CRLLEQETPV TLEALADQVA MSPFHLHRLF 120
  121 KATTGMTPKA WQQAWRARRL RESLAKGESV TTSILNAGFP DSSSYYRKAD ETLGMTAKQF 180
  181 RHGGENLAVR YALADCELGR CLVAESERGI CAILLGDDDA TLISELQQMF PAADNAPADL 240
  241 MFQQHVREVI ASLNQRDTPL TLPLDIRGTA FQQQVWQALR TIPCGETVSY QQLANAIGKP 300
  301 KAVRAVASAC AANKLAIIIP CHRVVRGDGT LSGYRWGVSR KAQLLRREAE NEER

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..174] PSI-BLAST 33.522879 Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
    2 View Details [175..354] PSI-BLAST 34.69897 ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • methylated-DNA-[protein]-cysteine S-methyltransferase activity
    		•  3.81641972619245 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.06900146562384 bayes_pls_golite062009
  • DNA binding
    		•  2.96596668208419 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.92705798633591 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  2.66007025371147 bayes_pls_golite062009
  • transcription factor activity
    		•  2.45682731123393 bayes_pls_golite062009
  • catalytic activity
    		•  1.90838528948382 bayes_pls_golite062009
  • binding
    		•  1.9004221787372 bayes_pls_golite062009
  • transferase activity
    		•  1.22815682532854 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.14625481859451 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.13184530961695 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle