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Protein Overview: C71AE_ARATH

General Information:
Name(s) found: C71AE_ARATH [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Cytochrome P450 71A14 OS=Arabidopsis thaliana GN=CYP71A14 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 497 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    Biological Process: NONE FOUND
    Molecular Function: oxygen binding [ISS]
    iron ion binding [IEA]
    electron carrier activity [IEA]
    monooxygenase activity [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMIIISLCL ATILALLLLK QFLNRTYTAK VNLPPSPWRV PVIGNLHQLS LHPHRSLRSL  60
   61 SHRYGPLMLL HFGRVPVLVV SSSDVAHDLM KTHDLKVANR PQLKVVEKIF NGGREMVFSP 120
  121 YGEYWRQIKS VCIVNLLNKK KVQSFEKVRE EEISEMMERV EKASSDSSPL NLSELLLTLT 180
  181 SDVTSRVSLG RKYSKEESMS DFKIQMRKIT ELVGGFPVGE YIPCLAWIDK LRGVDEKAEE 240
  241 VSKAFGDLME KVLQEHLDAT DKPTLDFVDV LLSLERHERN GVQIRRSDIK FLILDMFLAG 300
  301 TETTYALLEW IMTELIRHPE CMKKLQDEIR AKATKLILYI SEEDVEDMKY LKAVVKEVLR 360
  361 LHPPLPLLVP RELSEDIKLK GYDIAAGTQV IINAWAIQRD TMTWGIDAEE FRPERHLDSL 420
  421 VDFRGTNFEF IPFGSGRRIC PGIGFAMALV EVTLANLVNR FNWRMEVQHS GDEYDLAEST 480
  481 GLDVCRKFPL IVFPSPA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..497] PSI-BLAST 106.0 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • monooxygenase activity
    		•  4.68917162030329 bayes_pls_golite062009
  • electron carrier activity
    		•  4.64931978461551 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  4.24330950518208 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  2.60901411823382 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • oxygen binding
    		•  2.18573646076314 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.00587035559143 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  1.71233606135238 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • binding
    		•  1.64731849428898 bayes_pls_golite062009
  • retinoic acid binding
    		•  1.55035199545719 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  1.18865173999816 bayes_pls_golite062009
  • arachidonic acid monooxygenase activity
    		•  1.08222474610617 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  0.843305965220103 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  0.44276157912762 bayes_pls_golite062009
  • demethylase activity
    		•  0.297054031559449 bayes_pls_golite062009
  • retinoid binding
    		•  0.111941744968536 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.0595388458478079 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  0.0181579856816677 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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