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Protein Overview: nhr-1

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..155] PSI-BLAST 25.522879 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
2 View Details [156..445] PSI-BLAST 42.154902 Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2
Term Confidence Notes
  • transcription regulator activity
  • 5.53061626347066 bayes_pls_golite062009
  • DNA binding
  • 4.92165988569962 bayes_pls_golite062009
  • steroid hormone receptor activity
  • 4.81441024181511 bayes_pls_golite062009
  • nucleic acid binding
  • 4.78024150262074 bayes_pls_golite062009
  • transcription activator activity
  • 4.53302455129434 bayes_pls_golite062009
  • sequence-specific DNA binding
  • 4.11614358606713 bayes_pls_golite062009
  • transcription factor activity
  • 4.0914094580319 bayes_pls_golite062009
  • nuclear hormone receptor binding
  • 3.91470119037087 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
  • 3.89763470197726 bayes_pls_golite062009
  • binding
  • 3.85318710398432 bayes_pls_golite062009
  • transcription repressor activity
  • 3.83878598697109 bayes_pls_golite062009
  • hormone receptor binding
  • 3.79647267365529 bayes_pls_golite062009
  • molecular transducer activity
  • 3.57626193382263 bayes_pls_golite062009
  • signal transducer activity
  • 3.57626193382263 bayes_pls_golite062009
  • receptor activity
  • 3.45094937361521 bayes_pls_golite062009
  • protein binding
  • 3.21524787168952 bayes_pls_golite062009
  • transcription activator binding
  • 2.98235973123409 bayes_pls_golite062009
  • estrogen receptor activity
  • 2.84886725099086 bayes_pls_golite062009
  • transcription factor binding
  • 2.68044489404568 bayes_pls_golite062009
  • ecdysteroid hormone receptor activity
  • 2.54335605534182 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
  • 2.38308182853979 bayes_pls_golite062009
  • transcription coactivator activity
  • 2.27959329058894 bayes_pls_golite062009
  • hormone binding
  • 2.22128813425565 bayes_pls_golite062009
  • transcription cofactor activity
  • 1.73827483890179 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.70383793233433 bayes_pls_golite062009
  • retinoic acid receptor binding
  • 1.59968001933699 bayes_pls_golite062009
  • retinoid binding
  • 1.57244905045132 bayes_pls_golite062009
  • estrogen response element binding
  • 1.56094639526803 bayes_pls_golite062009
  • double-stranded DNA binding
  • 1.48246587604476 bayes_pls_golite062009
  • isoprenoid binding
  • 1.45798199211445 bayes_pls_golite062009
  • retinoid X receptor binding
  • 1.45560845709347 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
  • 1.34794228300778 bayes_pls_golite062009
  • promoter binding
  • 1.28787959668198 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
  • 1.23181585568439 bayes_pls_golite062009
  • transcription corepressor activity
  • 0.995333369475571 bayes_pls_golite062009
  • steroid binding
  • 0.933060984463406 bayes_pls_golite062009
  • retinoic acid receptor activity
  • 0.853869057774515 bayes_pls_golite062009
  • protein dimerization activity
  • 0.797229273848179 bayes_pls_golite062009
  • steroid hormone receptor binding
  • 0.754240851368212 bayes_pls_golite062009
  • retinoic acid binding
  • 0.676688935879073 bayes_pls_golite062009
  • protein N-terminus binding
  • 0.57701453824007 bayes_pls_golite062009
  • thyroid hormone receptor activity
  • 0.49784404390361 bayes_pls_golite062009
  • lipid binding
  • 0.475303782949439 bayes_pls_golite062009
  • protein heterodimerization activity
  • 0.45265806678057 bayes_pls_golite062009
  • vitamin D3 receptor activity
  • 0.428420599209378 bayes_pls_golite062009
  • receptor binding
  • 0.418843034756825 bayes_pls_golite062009
  • androgen receptor activity
  • 0.399730816072004 bayes_pls_golite062009
  • ligand-regulated transcription factor activity
  • 0.202197503742221 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
  • 0.15737167800277 bayes_pls_golite062009
  • catalytic activity
  • 0.106902059021677 bayes_pls_golite062009
  • androgen binding
  • 0.0219623894804069 bayes_pls_golite062009




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle