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Protein Overview: klc-2

General Information:
Name(s) found: klc-2 / CE32802 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00002215 locus:klc-2 Kinesin light chain status:Confirmed UniProt:P46822 protein_id:CCD65111.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 540 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    cytoplasm [IDA]
    kinesin I complex [IPI]
    kinesin complex [IEALink to PubMed article]
    Biological Process: synaptic vesicle transport [IPI]
    locomotion [IMP]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    oviposition [IMP]
    Molecular Function: microtubule motor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNMSQDDVT TGLRTVQQGL EALREEHSTI SNTLETSVKG VKEDEAPLPK QKLSQINDNL  60
   61 DKLVCGVDET SLMLMVFQLT QGMDAQHQKY QAQRRRLCQE NAWLRDELSS TQIKLQQSEQ 120
  121 MVAQLEEENK HLKYMASIKQ FDDGTQSDTK TSVDVGPQPV TNETLQELGF GPEDEEDMNA 180
  181 SQFNQPTPAN QMAASANVGY EIPARLRTLH NLVIQYASQG RYEVAVPLCK QALEDLEKTS 240
  241 GHDHPDVATM LNILALVYRD QNKYKEAANL LNEALSIREK CLGESHPAVA ATLNNLAVLF 300
  301 GKRGKFKDAE PLCKRALEIR EKVLGDDHPD VAKQLNNLAL LCQNQGKYEE VEKYYKRALE 360
  361 IYESKLGPDD PNVAKTKNNL SSAYLKQGKY KEAEELYKQI LTRAHEREFG QISGENKPIW 420
  421 QIAEEREENK HKGEGATANE QAGWAKAAKV DSPTVTTTLK NLGALYRRQG KYEAAETLED 480
  481 VALRAKKQHE PLRSGAMGGI DEMSQSMMAS TIGGSRNSMT TSTSQTGLKN KLMNALGFNS 540
  541

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run knl-1 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] MSA 1.481993 View MSA. No confident structure predictions are available.
    2 View Details [91..156] PSI-BLAST 4.69897 Clathrin D6 Coat
    3 View Details [157..540] PSI-BLAST 40.69897 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.14253214573541 bayes_pls_golite062009
  • protein binding
    		•  1.65083457326273 bayes_pls_golite062009
  • signal sequence binding
    		•  0.49295886046194 bayes_pls_golite062009
  • peroxisome targeting sequence binding
    		•  0.0468412220974996 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle