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View Structure Prediction Details

Protein: klc-2
Organism: Caenorhabditis elegans
Length: 540 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for klc-2.

Description E-value Query
Range
Subject
Range
gi|113476999, gi... - gi|113476999|ref|YP_723060.1| peptidase-like [Trichodesmium erythraeum IMS101], gi|110168047|gb|ABG5...
364.0 [0..5] [530..218]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNMSQDDVT TGLRTVQQGL EALREEHSTI SNTLETSVKG VKEDEAPLPK QKLSQINDNL  60
   61 DKLVCGVDET SLMLMVFQLT QGMDAQHQKY 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [91-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAQRRRLCQE NAWLRDELSS TQIKLQQSEQ MVAQLEEENK HLKYMASIKQ FDDGTQSDTK  60
   61 TSVDVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1xi4A
Description: Clathrin D6 Coat
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [157-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPVTNETLQ ELGFGPEDEE DMNASQFNQP TPANQMAASA NVGYEIPARL RTLHNLVIQY  60
   61 ASQGRYEVAV PLCKQALEDL EKTSGHDHPD VATMLNILAL VYRDQNKYKE AANLLNEALS 120
  121 IREKCLGESH PAVAATLNNL AVLFGKRGKF KDAEPLCKRA LEIREKVLGD DHPDVAKQLN 180
  181 NLALLCQNQG KYEEVEKYYK RALEIYESKL GPDDPNVAKT KNNLSSAYLK QGKYKEAEEL 240
  241 YKQILTRAHE REFGQISGEN KPIWQIAEER EENKHKGEGA TANEQAGWAK AAKVDSPTVT 300
  301 TTLKNLGALY RRQGKYEAAE TLEDVALRAK KQHEPLRSGA MGGIDEMSQS MMASTIGGSR 360
  361 NSMTTSTSQT GLKNKLMNAL GFNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.69897
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009
signal sequence binding 0.49295886046194 bayes_pls_golite062009
peroxisome targeting sequence binding 0.0468412220974996 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle