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Protein Overview: vhp-1

General Information:
Name(s) found: vhp-1 / CE32357 [WormBase]
Description(s) found:
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  • WBGene00006923 locus:vhp-1 Tyrosine-protein phosphatase vhp-1 status:Partially_confirmed UniProt:Q10038 protein_id:CCD68975.1 [WormBase]
  • gi|32563972|ref|NP_871926.1| VH1 dual-specificity phosphatase family member (vhp-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|24636102|gb|AAN63417.1| Vh1 dual-specificity phosphatase family protein 1, isoform c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed SW:Q10038 protein_id:AAN63417.1 [wormpep150.fasta]
  • 32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed TR:Q8IG35 protein_id:AAN63417.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • nose Resistant to Fluoxetine (Prozac) NRF-2, VH1 dual-specificity phosphatase (46.9 kD) (nrf-2) [Caenorhabditis elegans]gi|24636102|gb|AAN63417.1| Vh1 dual-specificity phosphatase family protein 1, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed TR:Q8IG35 protein_id:AAN63417.1 [wormpep132.fasta]
  • 32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed SW:Q10038 protein_id:AAN63417.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:vhp-1 status:Partially_confirmed TR:Q8IG35 protein_id:AAN63417.1 [wormpep115.fasta.reversed]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed UniProt:VHP1_CAEEL protein_id:AAN63417.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed UniProt:VHP1_CAEEL protein_id:AAN63417.1| [wormORF-contam.fasta]
  • VH1 dual-specificity phosphatase family member (vhp-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Vh1 dual-specificity phosphatase family protein 1, isoform c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed UniProt:Q10038 protein_id:AAN63417.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed UniProt:Q10038 protein_id:CCD68975.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE32357 WBGene00006923 locus:vhp-1 status:Partially_confirmed UniProt:Q10038 protein_id:CCD68975.1 Tyrosine-protein phosphatase vhp-1 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q10038, Isoform c of Tyrosine-protein phosphatase vhp-1 OS=Caenorhabditis elegans GN=vhp-1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    Biological Process: inactivation of MAPK activity [IDALink to PubMed article][IGILink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    protein amino acid dephosphorylation [IDALink to PubMed article][IEALink to PubMed article]
    response to copper ion [IGILink to PubMed article]
    negative regulation of JNK cascade [IDALink to PubMed article]
    dephosphorylation [IEALink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: protein tyrosine phosphatase activity [IEALink to PubMed article]
    phosphatase activity [IEALink to PubMed article]
    JUN kinase phosphatase activity [IDALink to PubMed article]
    MAP kinase tyrosine/serine/threonine phosphatase activity [IDALink to PubMed article]
    protein tyrosine/serine/threonine phosphatase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRLPQSLSQ PCLSQPTGDG ITLITPNIYL GSQIDSLDET MLDALDISVV INLSMTCPKS  60
   61 VCIKEDKNFM RIPVNDSYQE KLSPYFPMAY EFLEKCRRAG KKCLIHCLAG ISRSPTLAIS 120
  121 YIMRYMKMGS DDAYRYVKER RPSISPNFNF MGQLLEYENV LIKDHVLDYN QASRPHRHMD 180
  181 YYGPSDLCPP KVPKSASSNC VFPGSTHDES SPSSPSVSEG SAASEPETSS SAASSSSTAS 240
  241 APPSMPSTSE QGTSSGTVNV NGKRNMTMDL GLPHRPKALG LPSRIGTSVA ELPSPSTELS 300
  301 RLSFNGPEAI APSTPILNFT NPCFNSPIIP VASSSREVIL TLPTPAASSS SSTSSEPSFD 360
  361 FSSFESSSSS SIVVENPFFA STEVPAGSSS ISTPSGSQST PASASSSAAS RCRMKGFFKV 420
  421 FSKKAPASTS TPVSIMKLH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..172] PSI-BLAST 50.69897 No description for 2hxpA was found.
    2 View Details [173..261] deduced N/A No confident structure predictions are available.
    3 View Details [262..439] MSA 6.163996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle