YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: nhr-66

General Information:
Name(s) found: nhr-66 / CE31063 [WormBase]
Description(s) found:
Found 16 descriptions.
SHOW ALL
  • WBGene00003656 locus:nhr-66 status:Partially_confirmed UniProt:H2KYJ8 protein_id:CCD63564.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 733 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPINEPTAT TTSASSVWQG MTQLKSQVDL INIARGILST PATTSTSCLD IQNSTPIIGS  60
   61 LASGKSQTPI LTATMTPQIG LTGLGSLTSL PPELLLQFAR LDGFNLLPAV GSPAIPSSSS 120
  121 CSEPSTSQAS TVVSAPTLPP PSPLTSLPQK PAPLMPSGHV TTVDQQNRQQ HQQQQRQQQQ 180
  181 AQQQNSMARK YSMDTIQHHT MQHPHQLQYI PNHFMTASTD VFAAMDMSQK QSSPPGIFKI 240
  241 VAAKNEPSSS SNSQPGTPAM GDRRAVPACA ICGTDSTGIH FGVDACAACS AFFRRTVVLN 300
  301 KDYSCNKGGK CTVVKDGSAG QKCRACRFRK CISSGMDKNS VQHRRDAIGK YSAGVKRELS 360
  361 PDAEFEPSAK VSTVSEPSTS SGPSGGFNQN VSSPAGIPRV PSTLRTTQAS TCMNSACGQK 420
  421 SVLHELICRQ NFLTEQRQLF YAGCLGDWFR KPSSIENQTL SELTDFSSCM FHLWKIEPRL 480
  481 AADFMNRNRY LDPLPIVEKL KIYRNFVIMR QSVEEPYLTW RHGGLEKRWF VMPNNTYIDF 540
  541 NNIAKYFENG ALKDLKLDYE TTTNLFLPSF THAMDTIGEK MKKNNITETE LTILLGLVLL 600
  601 DPGIYGIHES TRKFLKRIRD QLIHDVYMYY EDEMSHLYDP EIRMADIFML VAAIKIHSIK 660
  661 TSENMHMLRV FDLIPADACF NQMLDVESVN VSPDGQKDSE AEQGPSPVSV PEAARGSYQD 720
  721 DDMPPVLEKN CDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] MSA 12.205997 View MSA. No confident structure predictions are available.
    2 View Details [191..265] deduced N/A No confident structure predictions are available.
    3 View Details [266..357] PSI-BLAST 23.69897 Crystal Structure of Vitmain D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element
    4 View Details [358..733] PSI-BLAST 60.0 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.31508164334985 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.02157665604796 bayes_pls_golite062009
  • DNA binding
    		•  1.47175550190876 bayes_pls_golite062009
  • signal transducer activity
    		•  1.430912689846 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.430912689846 bayes_pls_golite062009
  • protein binding
    		•  1.34648900580465 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.29377568150934 bayes_pls_golite062009
  • receptor activity
    		•  1.17902442273252 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  1.16718542519809 bayes_pls_golite062009
  • transcription activator activity
    		•  0.96843436755116 bayes_pls_golite062009
  • transcription factor activity
    		•  0.92060883178562 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.67007540744134 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle