| Protein: | nhr-66 |
| Organism: | Caenorhabditis elegans |
| Length: | 733 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-66.
| Description | E-value | Query Range |
Subject Range |
|
|
372.0 | [0..76] | [729..275] |
|
Region A: Residues: [1-190] |
1 11 21 31 41 51
| | | | | |
1 MPPINEPTAT TTSASSVWQG MTQLKSQVDL INIARGILST PATTSTSCLD IQNSTPIIGS 60
61 LASGKSQTPI LTATMTPQIG LTGLGSLTSL PPELLLQFAR LDGFNLLPAV GSPAIPSSSS 120
121 CSEPSTSQAS TVVSAPTLPP PSPLTSLPQK PAPLMPSGHV TTVDQQNRQQ HQQQQRQQQQ 180
181 AQQQNSMARK
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [191-265] |
1 11 21 31 41 51
| | | | | |
1 YSMDTIQHHT MQHPHQLQYI PNHFMTASTD VFAAMDMSQK QSSPPGIFKI VAAKNEPSSS 60
61 SNSQPGTPAM GDRRA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [266-357] |
1 11 21 31 41 51
| | | | | |
1 VPACAICGTD STGIHFGVDA CAACSAFFRR TVVLNKDYSC NKGGKCTVVK DGSAGQKCRA 60
61 CRFRKCISSG MDKNSVQHRR DAIGKYSAGV KR
|
| Detection Method: | |
| Confidence: | 23.69897 |
| Match: | 1ynwB |
| Description: | Crystal Structure of Vitmain D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [358-733] |
1 11 21 31 41 51
| | | | | |
1 ELSPDAEFEP SAKVSTVSEP STSSGPSGGF NQNVSSPAGI PRVPSTLRTT QASTCMNSAC 60
61 GQKSVLHELI CRQNFLTEQR QLFYAGCLGD WFRKPSSIEN QTLSELTDFS SCMFHLWKIE 120
121 PRLAADFMNR NRYLDPLPIV EKLKIYRNFV IMRQSVEEPY LTWRHGGLEK RWFVMPNNTY 180
181 IDFNNIAKYF ENGALKDLKL DYETTTNLFL PSFTHAMDTI GEKMKKNNIT ETELTILLGL 240
241 VLLDPGIYGI HESTRKFLKR IRDQLIHDVY MYYEDEMSHL YDPEIRMADI FMLVAAIKIH 300
301 SIKTSENMHM LRVFDLIPAD ACFNQMLDVE SVNVSPDGQK DSEAEQGPSP VSVPEAARGS 360
361 YQDDDMPPVL EKNCDL
|
| Detection Method: | |
| Confidence: | 60.0 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.31508164334985 | bayes_pls_golite062009 |
| transcription regulator activity | 2.02157665604796 | bayes_pls_golite062009 |
| DNA binding | 1.47175550190876 | bayes_pls_golite062009 |
| signal transducer activity | 1.430912689846 | bayes_pls_golite062009 |
| molecular transducer activity | 1.430912689846 | bayes_pls_golite062009 |
| protein binding | 1.34648900580465 | bayes_pls_golite062009 |
| nucleic acid binding | 1.29377568150934 | bayes_pls_golite062009 |
| receptor activity | 1.17902442273252 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.16718542519809 | bayes_pls_golite062009 |
| transcription activator activity | 0.96843436755116 | bayes_pls_golite062009 |
| transcription factor activity | 0.92060883178562 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.67007540744134 | bayes_pls_golite062009 |
