Protein Overview: CE21988

General Information:
Name(s) found:	CE21988 [WormBase]
Description(s) found: Found 17 descriptions. SHOW ALL	WBGene00012904 locus:tiar-2 status:Partially_confirmed UniProt:Q9U2F5 protein_id:CAB60356.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	434 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	mRNA processing [IEA]
Molecular Function:	nucleic acid binding [IEA] RNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSFYTGGG EDGDGFNPRV HARIAEREGF QLASGSEDPR TLFVANLDPA ITDEFLATLF  60
   61 NQIGAVMKAK IIFEGLNDPY AFVEFSDHNQ ATLALQSHNG RELLEKEMHV TWAFEPREPG 120
  121 ENRSKPETSR HFHVFVGDLC SEIDSTKLRE AFVKFGEVSE AKIIRDNNTN KGKGYGFVSY 180
  181 PRREDAERAI DEMNGAWLGR RTIRTNWATR KPDEDGERGG DRGDRRGGGG GGRDRYHNQS 240
  241 EKTYDEIFNQ AAADNTSVYV GNIANLGEDE IRRAFDRFGP INEVRTFKIQ GYAFVKFETK 300
  301 ESAARAIVQM NNADIGGQIV RCSWGKSGDS GKPSERGSGG GGGSGNYGYG YGNSGGGGGS 360
  361 GGPGNSQFSN FNQRPPPSGN GGSGGGSGGQ NNQYWQYYSQ YYNNPHLMQQ WNNYWQKDGP 420
  421 PPPPAAAASS TGGN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..211]	PSI-BLAST	47.0	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
2	View Details	[212..341]	FFAS03	4.53	No description for 2bz2A was found.
3	View Details	[342..434]	PSI-BLAST	3.09691	Sec24

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
RNA binding	5.15097136329571	bayes_pls_golite062009
nucleic acid binding	4.92126426323641	bayes_pls_golite062009
mRNA binding	4.05281507540116	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
	2.60920363363072	bayes_pls_golite062009
transcription regulator activity	2.18211199677674	bayes_pls_golite062009
DNA binding	1.98418556946403	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
poly-pyrimidine tract binding	1.36691748240059	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription factor activity	1.07843408116687	bayes_pls_golite062009
mRNA 3'-UTR binding	0.824614388276642	bayes_pls_golite062009
sequence-specific DNA binding	0.383589644462932	bayes_pls_golite062009

2

Term	Confidence	Notes
RNA binding	4.74219150342477	bayes_pls_golite062009
nucleic acid binding	4.65259034341669	bayes_pls_golite062009
mRNA binding	3.63162433534903	bayes_pls_golite062009
binding	3.48033873254013	bayes_pls_golite062009
	2.38034004712143	bayes_pls_golite062009
transcription regulator activity	2.2045206027152	bayes_pls_golite062009
DNA binding	1.99030664201171	bayes_pls_golite062009
transcription factor activity	1.09958329302628	bayes_pls_golite062009
single-stranded RNA binding	1.08300488237934	bayes_pls_golite062009
protein binding	1.05805521997665	bayes_pls_golite062009
poly-pyrimidine tract binding	0.960399311787502	bayes_pls_golite062009
mRNA 3'-UTR binding	0.462558743683805	bayes_pls_golite062009
sequence-specific DNA binding	0.327072171076297	bayes_pls_golite062009

3

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle