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View Structure Prediction Details

Protein: CE21988
Organism: Caenorhabditis elegans
Length: 434 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE21988.

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
311.0 [0..3] [433..43]

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Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSFYTGGG EDGDGFNPRV HARIAEREGF QLASGSEDPR TLFVANLDPA ITDEFLATLF  60
   61 NQIGAVMKAK IIFEGLNDPY AFVEFSDHNQ ATLALQSHNG RELLEKEMHV TWAFEPREPG 120
  121 ENRSKPETSR HFHVFVGDLC SEIDSTKLRE AFVKFGEVSE AKIIRDNNTN KGKGYGFVSY 180
  181 PRREDAERAI DEMNGAWLGR RTIRTNWATR K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
2.60920363363072 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 1.36691748240059 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [212-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDEDGERGGD RGDRRGGGGG GRDRYHNQSE KTYDEIFNQA AADNTSVYVG NIANLGEDEI  60
   61 RRAFDRFGPI NEVRTFKIQG YAFVKFETKE SAARAIVQMN NADIGGQIVR CSWGKSGDSG 120
  121 KPSERGSGGG 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.53
Match: 2bz2A
Description: No description for 2bz2A was found.

Predicted functions:

Term Confidence Notes
RNA binding 4.74219150342477 bayes_pls_golite062009
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
mRNA binding 3.63162433534903 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
2.38034004712143 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.99030664201171 bayes_pls_golite062009
transcription factor activity 1.09958329302628 bayes_pls_golite062009
single-stranded RNA binding 1.08300488237934 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
poly-pyrimidine tract binding 0.960399311787502 bayes_pls_golite062009
mRNA 3'-UTR binding 0.462558743683805 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [342-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGSGNYGYGY GNSGGGGGSG GPGNSQFSNF NQRPPPSGNG GSGGGSGGQN NQYWQYYSQY  60
   61 YNNPHLMQQW NNYWQKDGPP PPPAAAASST GGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle