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Protein Overview: dea2

General Information:
Name(s) found: dea2 / SPBC1198.02 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • adenine deaminase Dea2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 367 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: purine salvage [IDALink to PubMed article]
    adenine catabolic process [IDALink to PubMed article]
    purine ribonucleoside monophosphate biosynthetic process [IEA]
    nucleotide metabolic process [IEA]
    Molecular Function: adenine deaminase activity [IDALink to PubMed article]
    adenosine deaminase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNLPIYNFI RKLPKCEHHV HLEGCLSPDL VFRLAKKNGI TLPSDDAAYT TPSTLLASYE  60
   61 HFGCLDDFLR YYYIAVSVLI EASDFEALAY EYFSIAHSQG VHHAEVFFDP QTHTSRGISY 120
  121 DVVVSGFSAA CERANRDFGM STNLIMCFLR HLPSEAAHET FAEALKRNDF ENGIVAGVGL 180
  181 DSSEVDFPPE LFQEVYKLAA EKGIRRTGHA GEEGDPSYIR SGLDNLSLQR IDHGIRLVED 240
  241 KELMKRVAEE NIMLTMCPLS NLKLRCVNSI AELPVREFLE AGVPFSINCD DPAYFGGYTL 300
  301 ENYFAIQKHF NLTVKEWVFI ANAAINGSWI SGKRKEELLS SVQKCVKEYT AEIQQPKTLE 360
  361 TAVEVQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..367] PSI-BLAST 65.69897 HIV-1 Tat protein derived N-terminal nonapeptide Trp2-Tat(1-9) bound to the active site of Dipeptidyl peptidase IV (CD26)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • purine nucleoside binding
    		•  5.77008212157543 bayes_pls_golite062009
  • adenosine deaminase activity
    		•  4.58148305437166 bayes_pls_golite062009
  • adenine deaminase activity
    		•  3.70002828902508 bayes_pls_golite062009
  • hydrolase activity
    		•  3.62199995345412 bayes_pls_golite062009
  • dihydropyrimidinase activity
    		•  3.41635858763209 bayes_pls_golite062009
  • deaminase activity
    		•  1.79186203771221 bayes_pls_golite062009
  • catalytic activity
    		•  1.70199291046899 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.60895003474033 bayes_pls_golite062009
  • binding
    		•  1.20793368650496 bayes_pls_golite062009
  • protein binding
    		•  0.928500526896831 bayes_pls_golite062009
  • guanine deaminase activity
    		•  0.861706835095856 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    		•  0.787370269329878 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.629962267754185 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.573107361273483 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.530552339840648 bayes_pls_golite062009
  • DNA binding
    		•  0.462348875991261 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.408989331337656 bayes_pls_golite062009
  • peptidase activity
    		•  0.356051335471361 bayes_pls_golite062009
  • dihydroorotase activity
    		•  0.203044795244555 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle