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Protein Overview: rpn7

General Information:
Name(s) found: rpn7 / SPBC582.07c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • 19S proteasome regulatory subunit Rpn7 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 409 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    proteasome regulatory particle, base subcomplex [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    proteasome complex [IDALink to PubMed article]
    nuclear proteasome complex [IDALink to PubMed article]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [IMPLink to PubMed article]
    mitotic sister chromatid segregation [IMPLink to PubMed article]
    proteasome localization [IGILink to PubMed article]
    regulation of cell cycle [RCALink to PubMed article]
    proteasome assembly [IGILink to PubMed article]
    mitotic cell cycle [IMPLink to PubMed article]
    ubiquitin-dependent protein catabolic process [ISSLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCSPSATLTH RTMTEKARTV SDLTISQAIF ELSSPFLENK SQKALDTLFS AIRDHDLAPL  60
   61 YKYLSENPKT SASIDFDSNF LNSMIKKNEE KLAEFDKAIE DAQELNGEHE ILEAMKNKAD 120
  121 YYTNICDRER GVQLCDETFE RATLTGMKID VLFSKIRLAY VYADMRVVGQ LLEKLKPLIE 180
  181 KGGDWERKNR LKAYQGIYLM SIRNFSGAAD LLLDCMSTFS STELLPYYDV VRYAVISGAI 240
  241 SLDRVDVKTK IVDSPEVLAV LPQNESMSSL EACINSLYLC DYSGFFRTLA DVEVNHLKCD 300
  301 QFLVAHYRYY VREMRRRAYA QLLESYRALS IDSMAASFGV SVDYIDRDLA SFIPDNKLNC 360
  361 VIDRVNGVVF TNRPDEKNRQ YQEVVKQGDV LLNKLQKYQA TVMRGAFKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] deduced N/A No confident structure predictions are available.
    2 View Details [70..299] PSI-BLAST 5.522879 Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
    3 View Details [300..409] PSI-BLAST 11.69897 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  3.50995556050336 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.38144578566524 bayes_pls_golite062009
  • binding
    		•  3.33026160538031 bayes_pls_golite062009
  • DNA binding
    		•  3.30822066787723 bayes_pls_golite062009
  • transcription factor activity
    		•  2.60537570879007 bayes_pls_golite062009
  • hydrolase activity
    		•  2.30467124306022 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.32971938164691 bayes_pls_golite062009
  • transcription activator activity
    		•  1.08566311616647 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.95491822926452 bayes_pls_golite062009
  • protein binding
    		•  0.653872239015235 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.505349137311395 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.42135864069093 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.136726704233672 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.118016217031359 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle