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Protein Overview: SPCC553.02

General Information:
Name(s) found: SPCC553.02 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • glutamine-dependent NAD(+) synthetase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 700 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: NAD biosynthetic process [ISSLink to PubMed article]
    cellular nitrogen compound metabolic process [ICLink to PubMed article]
    Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [ISSLink to PubMed article]
    NAD+ synthase (glutamine-hydrolyzing) activity [ISSLink to PubMed article]
    ATP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERYVTIASC QLNQWAMDFE GNRLRIIDSI KEAKRQNASL RVGPELEVTG YGCEDHFLES  60
   61 DTYYHSWEML CSIIHDPDCQ DILLDIGMPV MHKAMRHNCR ILALNGKILL IRPKIWLCDD 120
  121 GNFRESRWFT PWLRPRVVET HYLPTFVAKS LNQTTVPIGD AILQCNETVV GVETCEELFT 180
  181 PNSPHIDMAL DGVEIFINAS GSHHELRKLT TRVNLIQNAT EKCGGIYLYS NQRGCDGGRL 240
  241 YYDGSSMIFA NGKMLAQGHQ FSLKDVEVIS ATVDVDTVRS YRFQPSHGIQ GVTRPSYERI 300
  301 HVNFSLSSYQ QDYDIYRKPT DPIEVTIPLP EEEITFGPAC WLWDYLRRSH AAGFFLPLSG 360
  361 GLDSCSTAVL VYSMCRIVCK AMEEDDAQVL SDVRRIVGDP SYSSTDPKKL LNHLFYTAFM 420
  421 GSEHSSKETR SRAKELSSLI GSYHTDVNID TMTSAVVKLF ALVTGKTPQF RSNGGTNAEN 480
  481 LALQNIQARS RMLLGYLFAQ LLPWVRGYSG SLLVLGSSNV DECLRGYLTK YDCSSADINP 540
  541 IGGISKTDLK SFLRYAKEAL DLPILQEFLD ATPTAELEPT TESYVQSDEA DMGMTYAELS 600
  601 VFGRLRKISK CGPYSMFTQL MHQWGDRLSP SQVAEKVKRF FHYYGINRHK MTTLTPSYHA 660
  661 ETYGVDDNRY DLRQFLYPSW TWQNKKIDAL ASKFEQHQRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..421] PSI-BLAST 63.221849 NIT-FHIT fusion protein, C-terminal domain; NIT-FHIT fusion protein, N-terminal domain
    2 View Details [422..700] PSI-BLAST 65.30103 NH3-dependent NAD+-synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  2.8930848757764 bayes_pls_golite062009
  • catalytic activity
    		•  1.64442398754697 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.35962310800332 bayes_pls_golite062009
  • binding
    		•  1.19055167016953 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.724655038971066 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ligase activity, forming carbon-nitrogen bonds
    		•  1.9422825865652 bayes_pls_golite062009
  • ligase activity
    		•  1.91098844584143 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  1.77152913449838 bayes_pls_golite062009
  • GMP synthase (glutamine-hydrolyzing) activity
    		•  1.08094655947236 bayes_pls_golite062009
  • catalytic activity
    		•  0.828867994386867 bayes_pls_golite062009
  • binding
    		•  0.752095595503409 bayes_pls_golite062009
  • NAD+ synthase activity
    		•  0.693146657234538 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.625929821763467 bayes_pls_golite062009
  • DNA binding
    		•  0.578102940811233 bayes_pls_golite062009
  • hydrolase activity
    		•  0.180852708655017 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle