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Protein Overview: Sep1-PA

General Information:
Name(s) found: Sep1-PA / FBpp0076897 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • The gene Septin-1 is referred to in FlyBase by the symbol Dmel\Sep1 (CG1403, FBgn0011710). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:21229303..21232715. It has the cytological map location 19F5. There is experimental evidence that it has the molecular function</span>: protein binding; ubiquitin protein ligase binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of apoptosis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 361 amino acids

    Gene Ontology:
    Cellular Component: germline ring canal [NAS]
    septin complex [IEA]
    septin ring [ISS]
    Biological Process: positive regulation of apoptosis [IDA]
    cytokinesis [ISS][NAS]
    cellularization [TAS]
    cell cycle [IEA]
    Molecular Function: GTP binding [ISS]
    protein binding [IPI]
    ubiquitin protein ligase binding [IPI]
    GTPase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTKGFSSI ETPGYVGFAN LPNQVHRKSV KKGFEFTLMV VGESGLGKST LVNSLFLTDL  60
   61 YPERIIPDAI EKQKQTVKLE ASTVEIEERG VKLRLTVVDT PGFGDAIDNS NSFGAILEYI 120
  121 DEQYERFLRD ESGLNRRNIV DNRIHCCFYF ISPFGHGLKP LDVEFMKKLH SKVNIVPVIA 180
  181 KADCLTKKEI LRLKCRIMQE IESHGIKIYP LPDCDSDEDE DYKEQVKQLK EAVPFAVCGA 240
  241 NTLLEVKGKK VRGRLYPWGV VEVENPDHCD FIKLRTMLIT HMQDLQEVTQ EVHYENYRSD 300
  301 RLAKGIKGKE NGVKAERDSS SQVVSNSVLG EKDRILQEKE AELRRMQEML AQMQARMQAQ 360
  361 Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..361] PSI-BLAST 94.154902 No description for 2qagA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle