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Protein Overview: Rnp4F-PD, Rnp4F-...

General Information:
Name(s) found: FBpp0309418 [FlyBase]
Rnp4F-PD / FBpp0111789 [FlyBase]
Rnp4F-PB / FBpp0089396 [FlyBase]
Rnp4F-PA / FBpp0070720 [FlyBase]
Description(s) found:
Found 52 descriptions.
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  • type=protein; loc=X:complement(5213169..5213615,5213687..5213789,5213846..5213966,5214031..5214537,5214592..5215536,5215595..5215770,5215852..5216360,5216423..5216440); ID=FBpp0309418; name=Rnp4F-PF; parent=FBgn0014024,FBtr0340477; dbxref=FlyBase:FBpp0309418,FlyBase_Annotation_IDs:CG3312-PF; MD5=45b62dc90f526d0fb886ec9edfa405b0; length=941; release=r5.56; species=Dmel; [FlyBase]
  • The gene RNA-binding protein 4F is referred to in FlyBase by the symbol Dmel\Rnp4F (CG3312, FBgn0014024). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5212961..5216759. It has the cytological map location 4F5. There is experimental evidence that it has the molecular function</span>: RNA binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; RNA processing. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene RNA-binding protein 4F is referred to in FlyBase by the symbol Dmel\Rnp4F (CG3312, FBgn0014024). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5212961..5216759. It has the cytological map location 4F5. There is experimental evidence that it has the molecular function</span>: RNA binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; RNA processing. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene RNA-binding protein 4F is referred to in FlyBase by the symbol Dmel\Rnp4F (CG3312, FBgn0014024). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5212961..5216759. It has the cytological map location 4F5. There is experimental evidence that it has the molecular function</span>: RNA binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; RNA processing. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 941 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: central nervous system development [IMP]
    RNA processing [IDA]
    Molecular Function: nucleotide binding [IEA]
    RNA binding [IPI]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDADKQLERQ LEKELDEMPA EDLDDDAYDE YDLIVIPDQG KGSPQQGHSE SPQQEEEHKS  60
   61 EELRQRSRPT WPPSSAGGDM TTIELISSDD EPSVEETEGG NAAGRGRARN DSSSSSDDVG 120
  121 VIEGSELESN SEVSSDSDSD SDNAGGGNQL ERSYQELNAL PSKKFAQMVS LIGIAFKLND 180
  181 LEKIESSVLE LQNLATVPAH VWLKYLKARL VVTQTDEERK AFEEQCAKAL GYYYSIPLSE 240
  241 YVVNYLVDQG NVQNHVLWAK LLADYDVERP DFGDKLRSLI STITDENEAA AFVEMLQKHC 300
  301 VTWTCNVEQR QMIKSVVDKF KQHLDETTRG WDWSEQHKAH VYDVETLSLD DDLKNAVIRF 360
  361 IFERSVAKFP IVDVLWLSYI EFIQFEGVTV PENEDENEVT AEMVAKRAKR LGKGFLRNTE 420
  421 LDLANRGVRS HPSVQLNHRF LDLMERSDFE LAEVDEEIRL ILQRIVTDMD MTVELHLDYL 480
  481 AYRIRNTNAS DEQQVASLRA AFNHAWEELT VLYGDQADTR YEVLQLWAQV EYTQLGSPDN 540
  541 GREIWRQIMG YPGSSIRGLL WLNFAQMESE YNGGHGTRDV LRKALSQPVL ENGLMVQEFF 600
  601 RRYERCYGTY ESIAACQALD LPVEYVKPRS RIKPNSQSAY PRQQKLKPRQ QQQQTNREPL 660
  661 NREQRRRQAH EQQQQQQQQQ KHGIKKSRTE PSGGATSPPS KVKGPANAEA KESNFKYSPN 720
  721 MEINKIFVRN LHPACSKEEL HELFSPFGTI KDVRLVHKLN KQFKGIAYVE FEKPGEAQRA 780
  781 VAGRDGCLFK GMNISVAISN PPPRGTSAVK PSVAPKRRVP TSLIPTTLVR QEVAAKKLRL 840
  841 LLPEPGDISS TSASVDVAIK REANGEEQKG DVQERDEQKG EEQKGEEQKG EEPKGEEQKG 900
  901 DDQIGEEQSG VEQKGDEKKE EEMPAAVPKS NDDFRKLFLK D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] deduced N/A No confident structure predictions are available.
    2 View Details [92..644] PSI-BLAST 54.30103 No description for 2ooeA was found.
    3 View Details [645..705] deduced N/A No confident structure predictions are available.
    4 View Details [706..941] PSI-BLAST 27.045757 Nuclear ribonucleoprotein A1 (RNP A1, UP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein binding
    		•  0.93235633671694 bayes_pls_golite062009
  • binding
    		•  0.787280988128024 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • RNA binding
    		•  3.06771312666314 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.20292754034443 bayes_pls_golite062009
  • binding
    		•  1.71154446874967 bayes_pls_golite062009
  • mRNA binding
    		•  1.67824071507664 bayes_pls_golite062009
  • protein binding
    		•  0.426607329742248 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle