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View Structure Prediction Details

Protein: Rnp4F-PD, Rnp4F-...
Organism: Drosophila melanogaster
Length: 941 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rnp4F-PD, Rnp4F-....

Description E-value Query
Range
Subject
Range
gi|2582672 - gi|2582672|emb|CAA75535.1| RNA binding protein [Drosophila melanogaster]
482.0 [0..1] [941..1]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDADKQLERQ LEKELDEMPA EDLDDDAYDE YDLIVIPDQG KGSPQQGHSE SPQQEEEHKS  60
   61 EELRQRSRPT WPPSSAGGDM TTIELISSDD E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [92-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSVEETEGGN AAGRGRARND SSSSSDDVGV IEGSELESNS EVSSDSDSDS DNAGGGNQLE  60
   61 RSYQELNALP SKKFAQMVSL IGIAFKLNDL EKIESSVLEL QNLATVPAHV WLKYLKARLV 120
  121 VTQTDEERKA FEEQCAKALG YYYSIPLSEY VVNYLVDQGN VQNHVLWAKL LADYDVERPD 180
  181 FGDKLRSLIS TITDENEAAA FVEMLQKHCV TWTCNVEQRQ MIKSVVDKFK QHLDETTRGW 240
  241 DWSEQHKAHV YDVETLSLDD DLKNAVIRFI FERSVAKFPI VDVLWLSYIE FIQFEGVTVP 300
  301 ENEDENEVTA EMVAKRAKRL GKGFLRNTEL DLANRGVRSH PSVQLNHRFL DLMERSDFEL 360
  361 AEVDEEIRLI LQRIVTDMDM TVELHLDYLA YRIRNTNASD EQQVASLRAA FNHAWEELTV 420
  421 LYGDQADTRY EVLQLWAQVE YTQLGSPDNG REIWRQIMGY PGSSIRGLLW LNFAQMESEY 480
  481 NGGHGTRDVL RKALSQPVLE NGLMVQEFFR RYERCYGTYE SIAACQALDL PVEYVKPRSR 540
  541 IKPNSQSAYP RQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.30103
Match: 2ooeA
Description: No description for 2ooeA was found.

Predicted functions:

Term Confidence Notes
protein binding 0.93235633671694 bayes_pls_golite062009
binding 0.787280988128024 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [645-705]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLKPRQQQQQ TNREPLNREQ RRRQAHEQQQ QQQQQQKHGI KKSRTEPSGG ATSPPSKVKG  60
   61 P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [706-941]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANAEAKESNF KYSPNMEINK IFVRNLHPAC SKEELHELFS PFGTIKDVRL VHKLNKQFKG  60
   61 IAYVEFEKPG EAQRAVAGRD GCLFKGMNIS VAISNPPPRG TSAVKPSVAP KRRVPTSLIP 120
  121 TTLVRQEVAA KKLRLLLPEP GDISSTSASV DVAIKREANG EEQKGDVQER DEQKGEEQKG 180
  181 EEQKGEEPKG EEQKGDDQIG EEQSGVEQKG DEKKEEEMPA AVPKSNDDFR KLFLKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.045757
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.06771312666314 bayes_pls_golite062009
nucleic acid binding 2.20292754034443 bayes_pls_golite062009
binding 1.71154446874967 bayes_pls_golite062009
mRNA binding 1.67824071507664 bayes_pls_golite062009
protein binding 0.426607329742248 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle