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Protein Overview: boi-PB, FBpp0292...

General Information:
Name(s) found: FBpp0292890 [FlyBase]
FBpp0292889 [FlyBase]
boi-PB / FBpp0070441 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • type=protein; loc=X:complement(2339084..2339626,2340444..2340610,2340675..2340857,2340923..2341630,2344703..2344871,2344936..2346162); ID=FBpp0292890; name=boi-PF; parent=FBgn0040388,FBtr0303887; dbxref=FlyBase:FBpp0292890,FlyBase_Annotation_IDs:CG32796-PF,REFSEQ:NP_001188541,GB_protein:ADV37625; MD5=975420b18ce0cc921fe41934acc7008c; length=998; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(2339084..2339626,2340444..2340610,2340675..2340857,2340923..2341630,2344703..2344871,2344936..2346162); ID=FBpp0292889; name=boi-PE; parent=FBgn0040388,FBtr0303886; dbxref=FlyBase:FBpp0292889,FlyBase_Annotation_IDs:CG32796-PE,REFSEQ:NP_001188540,GB_protein:ADV37624; MD5=975420b18ce0cc921fe41934acc7008c; length=998; release=r5.56; species=Dmel; [FlyBase]
  • The gene brother of iHog is referred to in FlyBase by the symbol Dmel\boi (CG32796, FBgn0040388). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2338197..2364036. It has the cytological map location 3A3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway. 18 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 998 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: smoothened signaling pathway [IMP]
    cell adhesion [ISS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEIRLVVVL LVLMTTCIYT LQASDSNSSV ATTLGVLFER APESAVAPKG DEVVFECELN  60
   61 LKPDRLEWRF RRGDSSEPYL YLRPSAGYNV TSGSDGLAWR LRIYVSAQTA GDYQCVAWYG 120
  121 PGALASTPAR LALVSIALDV GQGSMGARSS IRWSVAPKNC LLIRCGSVIS NPPAIWSFYR 180
  181 NGKKLPQSEL LPGAAGALVL DTVTAKDAGN YSCVATNSIT GDELRLPQTI ELRVDYTDRT 240
  241 PPYFLQRPPI EYSARPGETV VLECPGVGSP RPRVIWSSPN VVEIYNNRST ILSYGLQITD 300
  301 VKPEDQGSYI CMLDNGIAPP IDHTIKLSVL QRPTILRGPA ATLTNESNPL LLDCSASGNP 360
  361 QPDIYWLING EDATKDPEAV VDNRSLQLKR VQKRHAGVVQ CFAKNILGET SEGNILRVNP 420
  421 LEITGEDDEP LGEVPVWPVH ESNTGMGTSS TSGGSKNKSG RRKFKASMVP PSRPNVTRLS 480
  481 DESVMLRWSV PQNSGLQITF FKVQYRMLGD GKNRRKNWQT TSDNIPYGNA HGSGPGQGNS 540
  541 HWRARNRDRE YEMGNPPKNF TSSVTGLTAG KYYRFRIVAV YSNNDNKEGN TSLKFFLQNG 600
  601 TSKSNLPVPE LREVETLSES AVVLHWSLVS STQNEDIDGY YAYYRPADSA AEYLKATVDG 660
  661 GMSRSFKIDL LRPGTPYEFK LQSFNSDAAS EFSAIRQART RKTHEQPASS SATPVPANKA 720
  721 VEQHQNSLYP LIAGAAGGGI LLLIASLVVC LCLKRRENSQ PEDENKPQLE HIQADFVTSA 780
  781 VLGVGGHHKS GDVRRLNGVI PRMNITPNPL AQETASDKNN SGLHQNGLHH AQPYHPPGTP 840
  841 TLMHKRLDYH QQPPPVPPHS AYYQQAPTHQ PSPMMERSVR GHQQPGGFHM EEGTPTPTRI 900
  901 PSLRRQRRTS GNQQVHNSHS NLNIGLSHHN NNNNNLPPHH QHLHHHPGHP GGLVGIPIVP 960
  961 GSPRVQRSPM PSRAMIKRTR LGSHTDNISS GSLNSIEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..318] PSI-BLAST 68.30103 Axonin-1
    2 View Details [319..428] PSI-BLAST 6.154902 No description for 2edhA was found.
    3 View Details [429..604] PSI-BLAST 13.154902 No description for 2ibgA was found.
    4 View Details [605..925] PSI-BLAST 11.522879 Fibronectin, different Fn3 modules
    5 View Details [926..998] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor activity
    		•  4.00123250685257 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.81769911097805 bayes_pls_golite062009
  • signal transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • binding
    		•  2.53652619212064 bayes_pls_golite062009
  • protein binding
    		•  2.22855404705168 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  1.02428106476324 bayes_pls_golite062009
  • peptide binding
    		•  0.729048089532569 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.702377899903974 bayes_pls_golite062009
  • protein complex binding
    		•  0.50170410061385 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.50126790962583 bayes_pls_golite062009
  • peptide antigen binding
    		•  0.26030339229539 bayes_pls_golite062009
  • olfactory receptor activity
    		•  0.20101044847022 bayes_pls_golite062009
  • receptor binding
    		•  0.195186987186423 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.19434148613974 bayes_pls_golite062009
  • integrin binding
    		•  0.15934671558405 bayes_pls_golite062009
  • growth factor binding
    		•  0.0660665023345297 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transmembrane receptor activity
    		•  4.81256300373074 bayes_pls_golite062009
  • receptor activity
    		•  4.66147271961356 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.69234048247377 bayes_pls_golite062009
  • signal transducer activity
    		•  3.69234048247377 bayes_pls_golite062009
  • protein binding
    		•  3.24522318184038 bayes_pls_golite062009
  • cytokine binding
    		•  3.09643795820234 bayes_pls_golite062009
  • cytokine receptor activity
    		•  2.76876397305497 bayes_pls_golite062009
  • binding
    		•  2.48482256624718 bayes_pls_golite062009
  • growth factor binding
    		•  1.84802345981571 bayes_pls_golite062009
  • interleukin-6 receptor activity
    		•  1.35720028769065 bayes_pls_golite062009
  • interleukin-6 binding
    		•  1.35720028769065 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.14823792822309 bayes_pls_golite062009
  • peptide binding
    		•  0.92031154055894 bayes_pls_golite062009
  • receptor binding
    		•  0.87932210318836 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.676345290589742 bayes_pls_golite062009
  • peptide hormone binding
    		•  0.64261911609124 bayes_pls_golite062009
  • identical protein binding
    		•  0.564711394496051 bayes_pls_golite062009
  • cytokine receptor binding
    		•  0.27430241665208 bayes_pls_golite062009
  • ciliary neurotrophic factor receptor activity
    		•  0.0804366220043198 bayes_pls_golite062009
  • hormone binding
    		•  0.0678762405417499 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.0448215941587721 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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