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View Structure Prediction Details

Protein: boi-PB, FBpp0292...
Organism: Drosophila melanogaster
Length: 998 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for boi-PB, FBpp0292....

Description E-value Query
Range
Subject
Range
gi|109035924, gi... - gi|109035924|ref|XP_001101311.1| PREDICTED: similar to contactin 4 isoform a precursor isoform 3 [Ma...
475.0 [0..36] [916..26]

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Predicted Domain #1
Region A:
Residues: [1-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEIRLVVVL LVLMTTCIYT LQASDSNSSV ATTLGVLFER APESAVAPKG DEVVFECELN  60
   61 LKPDRLEWRF RRGDSSEPYL YLRPSAGYNV TSGSDGLAWR LRIYVSAQTA GDYQCVAWYG 120
  121 PGALASTPAR LALVSIALDV GQGSMGARSS IRWSVAPKNC LLIRCGSVIS NPPAIWSFYR 180
  181 NGKKLPQSEL LPGAAGALVL DTVTAKDAGN YSCVATNSIT GDELRLPQTI ELRVDYTDRT 240
  241 PPYFLQRPPI EYSARPGETV VLECPGVGSP RPRVIWSSPN VVEIYNNRST ILSYGLQITD 300
  301 VKPEDQGSYI CMLDNGIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.30103
Match: 1cs6A
Description: Axonin-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 4.00123250685257 bayes_pls_golite062009
transmembrane receptor activity 3.81769911097805 bayes_pls_golite062009
signal transducer activity 3.10913345555941 bayes_pls_golite062009
molecular transducer activity 3.10913345555941 bayes_pls_golite062009
binding 2.53652619212064 bayes_pls_golite062009
protein binding 2.22855404705168 bayes_pls_golite062009
G-protein coupled receptor activity 1.02428106476324 bayes_pls_golite062009
peptide binding 0.729048089532569 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.702377899903974 bayes_pls_golite062009
protein complex binding 0.50170410061385 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.50126790962583 bayes_pls_golite062009
peptide antigen binding 0.26030339229539 bayes_pls_golite062009
olfactory receptor activity 0.20101044847022 bayes_pls_golite062009
receptor binding 0.195186987186423 bayes_pls_golite062009
cell adhesion molecule binding 0.19434148613974 bayes_pls_golite062009
integrin binding 0.15934671558405 bayes_pls_golite062009
growth factor binding 0.0660665023345297 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [319-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPIDHTIKLS VLQRPTILRG PAATLTNESN PLLLDCSASG NPQPDIYWLI NGEDATKDPE  60
   61 AVVDNRSLQL KRVQKRHAGV VQCFAKNILG ETSEGNILRV NPLEITGEDD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.154902
Match: 2edhA
Description: No description for 2edhA was found.

Predicted Domain #3
Region A:
Residues: [429-604]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPLGEVPVWP VHESNTGMGT SSTSGGSKNK SGRRKFKASM VPPSRPNVTR LSDESVMLRW  60
   61 SVPQNSGLQI TFFKVQYRML GDGKNRRKNW QTTSDNIPYG NAHGSGPGQG NSHWRARNRD 120
  121 REYEMGNPPK NFTSSVTGLT AGKYYRFRIV AVYSNNDNKE GNTSLKFFLQ NGTSKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 2ibgA
Description: No description for 2ibgA was found.

Predicted Domain #4
Region A:
Residues: [605-925]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPVPELREV ETLSESAVVL HWSLVSSTQN EDIDGYYAYY RPADSAAEYL KATVDGGMSR  60
   61 SFKIDLLRPG TPYEFKLQSF NSDAASEFSA IRQARTRKTH EQPASSSATP VPANKAVEQH 120
  121 QNSLYPLIAG AAGGGILLLI ASLVVCLCLK RRENSQPEDE NKPQLEHIQA DFVTSAVLGV 180
  181 GGHHKSGDVR RLNGVIPRMN ITPNPLAQET ASDKNNSGLH QNGLHHAQPY HPPGTPTLMH 240
  241 KRLDYHQQPP PVPPHSAYYQ QAPTHQPSPM MERSVRGHQQ PGGFHMEEGT PTPTRIPSLR 300
  301 RQRRTSGNQQ VHNSHSNLNI G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 1fnhA
Description: Fibronectin, different Fn3 modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transmembrane receptor activity 4.81256300373074 bayes_pls_golite062009
receptor activity 4.66147271961356 bayes_pls_golite062009
molecular transducer activity 3.69234048247377 bayes_pls_golite062009
signal transducer activity 3.69234048247377 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
cytokine binding 3.09643795820234 bayes_pls_golite062009
cytokine receptor activity 2.76876397305497 bayes_pls_golite062009
binding 2.48482256624718 bayes_pls_golite062009
growth factor binding 1.84802345981571 bayes_pls_golite062009
interleukin-6 receptor activity 1.35720028769065 bayes_pls_golite062009
interleukin-6 binding 1.35720028769065 bayes_pls_golite062009
cell adhesion molecule binding 1.14823792822309 bayes_pls_golite062009
peptide binding 0.92031154055894 bayes_pls_golite062009
receptor binding 0.87932210318836 bayes_pls_golite062009
protein dimerization activity 0.676345290589742 bayes_pls_golite062009
peptide hormone binding 0.64261911609124 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
cytokine receptor binding 0.27430241665208 bayes_pls_golite062009
ciliary neurotrophic factor receptor activity 0.0804366220043198 bayes_pls_golite062009
hormone binding 0.0678762405417499 bayes_pls_golite062009
protein homodimerization activity 0.0448215941587721 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [926-998]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSHHNNNNNN LPPHHQHLHH HPGHPGGLVG IPIVPGSPRV QRSPMPSRAM IKRTRLGSHT  60
   61 DNISSGSLNS IEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle