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Protein Overview: Sox100B-PA

General Information:
Name(s) found: Sox100B-PA / FBpp0085097 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Sox100B is referred to in FlyBase by the symbol Dmel\Sox100B (CG15552, FBgn0024288). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26891079..26909129. It has the cytological map location 100B2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; DNA bending activity. There is experimental evidence that it is involved in the biological process</span>: male gonad development. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 529 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: male gonad development [IDA][IMP]
    regulation of transcription [ISS]
    Molecular Function: transcription factor activity [ISS]
    DNA bending activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSSSSNCS KDRAKPVETL VLANYALKAE QKKAQGQGGR KEDERITTAV MKVLEGYDWN  60
   61 LVQASAKAPT DRKKEHIKRP MNAFMVWAQA ARRVMSKQYP HLQNSELSKS LGKLWKNLKD 120
  121 SDKKPFMEFA EKLRMTHKQE HPDYKYQPRR KKARVLPSQQ SGEGGSPGPE MTLSATMGSS 180
  181 GKPRSSNSNG QRRAGKGNAA ADLGSCASTI SHANVGSNSS DVFSNEAFMK SLNSACAASL 240
  241 MEQSLIETGL DSPCSTASSM SSLTPPATPY NVAPSNAKAS AANNPSLLLR QLSEPVANAG 300
  301 DGYGVLLEAG REYVAIGEVN YQGQSAGVQS GAEGGGAGQE MDFLENINGY GGYTGSRVSY 360
  361 PAYSYPANGG HFATEEQQQQ QALQASEALN YKPAAADIDP KEIDQYFMDQ MLPMTQHHHP 420
  421 HHTHPLHHPL HHSPPLNSSA SLSSACSSAS SQQPVAEYYE HLGYSPAASS ASQNPNFGPQ 480
  481 QPYANGAASM TPTLGDPAPQ QELQSQQQEQ QHQNPSQHHL WGTYTYVNP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..81] PSI-BLAST 12.221849 NMR STRUCTURE OF RAT HMG1 HMGA FRAGMENT
    2 View Details [82..235] PSI-BLAST 26.0 No description for 2gzkA was found.
    3 View Details [236..349] deduced N/A No confident structure predictions are available.
    4 View Details [350..529] MSA 13.213997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA binding
    		•  5.15324651287773 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.9607192917135 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.70730250099648 bayes_pls_golite062009
  • transcription factor activity
    		•  3.82658263870186 bayes_pls_golite062009
  • binding
    		•  3.6211482127468 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.96229555092695 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.84606709725198 bayes_pls_golite062009
  • transcription activator activity
    		•  1.62744929149746 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.53825678633232 bayes_pls_golite062009
  • protein binding
    		•  1.131658134984 bayes_pls_golite062009
  • transcription factor binding
    		•  1.10315330167937 bayes_pls_golite062009
  • DNA bending activity
    		•  0.87985209274756 bayes_pls_golite062009
  • chromatin binding
    		•  0.830960835937769 bayes_pls_golite062009
    2
    Term Confidence Notes
  • DNA binding
    		•  5.15324651287773 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.9607192917135 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.70730250099648 bayes_pls_golite062009
  • transcription factor activity
    		•  3.82658263870186 bayes_pls_golite062009
  • binding
    		•  3.6211482127468 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.96229555092695 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.84606709725198 bayes_pls_golite062009
  • transcription activator activity
    		•  1.62744929149746 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.53825678633232 bayes_pls_golite062009
  • protein binding
    		•  1.131658134984 bayes_pls_golite062009
  • transcription factor binding
    		•  1.10315330167937 bayes_pls_golite062009
  • DNA bending activity
    		•  0.87985209274756 bayes_pls_golite062009
  • chromatin binding
    		•  0.830960835937769 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle