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Protein Overview: CG9589-PA

General Information:
Name(s) found: CG9589-PA / FBpp0082627 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG9589 (CG9589, FBgn0038361). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11614243..11615214. It has the cytological map location 89A5. Based on sequence similarity, it is predicted to have molecular function</span>: uroporphyrinogen-III synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: tetrapyrrole biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 253 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tetrapyrrole biosynthetic process [IEA]
    Molecular Function: uroporphyrinogen-III synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDRNKQPVI LLKVPSSDDF YGSALRSHNL DPIFITPSHF VFKNLKQLQA KLHEPHKYAG  60
   61 IIFASPRCVQ AVNEALGKTP LPSCWRALHN YSLGKNTHSA AWITFQNLPT LGDHAVNANN 120
  121 LCDLIVETFG PKRDLPLLMP CGNGVGQTLR LRLVAQGFRV DACEVYESRS HPDFVNQMRH 180
  181 ALKFKRMETI VFFGPSSVRS SLEFFGNYNV SLKDRKLIAV GSGTRKAMEE SGIKADGVVN 240
  241 AADVDRLINI IKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] PSI-BLAST 47.154902 Uroporphyrinogen III synthase (U3S, HemD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrinogen-III synthase activity
    		•  3.75954315324218 bayes_pls_golite062009
  • catalytic activity
    		•  1.13824203225664 bayes_pls_golite062009
  • binding
    		•  0.967564107266709 bayes_pls_golite062009
  • hydro-lyase activity
    		•  0.290711782955013 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle