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Protein Overview: Vps16A-PA

General Information:
Name(s) found: Vps16A-PA / FBpp0081459 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Vacuolar protein sorting 16A is referred to in FlyBase by the symbol Dmel\Vps16A (CG8454, FBgn0261241). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5092754..5095958. It has the cytological map location 85D7. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: autophagic vacuole fusion; eye pigment granule organization. 2 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; primary pigment cell pigment granule; secondary pigment cell pigment granule; pseudocone; pigment cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 833 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDA]
    Biological Process: lysosomal transport [NAS]
    eye pigment granule organization [IMP]
    intracellular protein transport [IEA]
    autophagic vacuole fusion [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIMYNTGEW FKVRPDYYRK VELATPDWPL DLDLEYMWVE VAPYGGPLAV TRDPTKLVPV  60
   61 KGNARPMIRI FDTTGREMGH ILWNHGKLIA MGWSDMEELI CIQENATVFV YDMFGREKES 120
  121 YSIGDEASVT KIVEGKVFQS SAGTGVAVMT TSGRVFLKQN SSKTERKLPD IPNSSMNCSC 180
  181 WEIVTEGRNS YCLLGRDREV IKLFPGETVG TITANLFEKP HERIIKISVS YNHQHLALYT 240
  241 NTGLLWLGSV DMRQKYCEFD TGRKDMPLQM EWIMNSDNSE ADAVVISYPS YLLIVNRNAD 300
  301 RSDFPYDPVM FLVAEMDGVR IITQSSHEII QRLPKCVENI FAVNSQEPAS YLFEAQKKFE 360
  361 EKSYKSDEYL SMCREKIDLA VSECIEAASY EFCPETQKSL LRTAYFGKGF IRNHNPDEYM 420
  421 RIMRILRVLN TLRHERIAMP ITFKQFSHLN TEVILSRLVF RKHYAIAIQV AKHLNLPESW 480
  481 ILEHWAYHKV MNDPNDTEVA RKITEKFKNP SVEGISFCNI ASKAHQAGRD DLAIKLLELE 540
  541 SRASLHVPLL LKMRKFDRAV GSATQSGDTE LITQVLLEMK MHMMLSNLHM TIRDHPLALN 600
  601 IYKKIMRESN RAGLYGIYNT EDDQKAIAEY HFQNAIETEG LESNLSMIGN AYAQGRCTLE 660
  661 AELCADTSRL IKLQKTLSTK YNVSLNGLSI HETIQELLLI GELKEAERIR SEFKVPDRRF 720
  721 WWLRILTLSS QHKWEELEKL AKSKKSPIGY DPFVEVCLKQ DNVMEARKYI PRCRDNRRVV 780
  781 WYMRANLFNE AIDSAFEQRD VHSLFELQKN QAIVNNGTLL SKVCDCIAML EGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..594] FFAS03 2.98 Actin interacting protein 1
    2 View Details [595..833] PSI-BLAST 5.0 Clathrin D6 Coat

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  2.36802077000866 bayes_pls_golite062009
  • binding
    		•  2.23598589443994 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.1136449999874 bayes_pls_golite062009
  • transporter activity
    		•  1.23232041140488 bayes_pls_golite062009
  • protein binding
    		•  1.16796757764458 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.750051725890322 bayes_pls_golite062009
  • actin filament binding
    		•  0.680577261614999 bayes_pls_golite062009
  • hydrolase activity
    		•  0.346903609858078 bayes_pls_golite062009
  • tubulin binding
    		•  0.291956397524181 bayes_pls_golite062009
  • microtubule binding
    		•  0.213830210314093 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0245411309982146 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle