Protein Overview: Mlp84B-PA, Mlp84B-PB

General Information:
Name(s) found:	Mlp84B-PB / FBpp0081134 [FlyBase] Mlp84B-PA / FBpp0081133 [FlyBase]
Description(s) found: Found 47 descriptions. SHOW ALL	The gene Muscle LIM protein at 84B is referred to in FlyBase by the symbol Dmel\Mlp84B (CG1019, FBgn0014863). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2939244..2943453. It has the cytological map location 84C1. There is experimental evidence that it has the molecular function</span>: structural constituent of muscle. There is experimental evidence that it is involved in the biological process</span>: sarcomere organization. 11 alleles are reported. The phenotype of these alleles is annotated with: pupal cuticle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene Muscle LIM protein at 84B is referred to in FlyBase by the symbol Dmel\Mlp84B (CG1019, FBgn0014863). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2939244..2943453. It has the cytological map location 84C1. There is experimental evidence that it has the molecular function</span>: structural constituent of muscle. There is experimental evidence that it is involved in the biological process</span>: sarcomere organization. 11 alleles are reported. The phenotype of these alleles is annotated with: pupal cuticle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	495 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS][NAS] Z disc [IDA] cytoplasm [NAS]
Biological Process:	skeletal muscle tissue development [NAS] cell differentiation [NAS] sarcomere organization [IGI]
Molecular Function:	zinc ion binding [IEA] protein binding [ISS] structural constituent of muscle [IGI][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSFQPIEAP KCPRCGKSVY AAEERLAGGY VFHKNCFKCG MCNKSLDSTN CTEHERELYC  60
   61 KTCHGRKFGP KGYGFGTGAG TLSMDNGSQF LRENGDVPSV RNGARLEPRA IARAPEGEGC 120
  121 PRCGGYVYAA EQMLARGRSW HKECFKCGTC KKGLDSILCC EAPDKNIYCK GCYAKKFGPK 180
  181 GYGYGQGGGA LQSDCYAHDD GAPQIRAAID VDKIQARPGE GCPRCGGVVY AAEQKLSKGR 240
  241 EWHKKCFNCK DCHKTLDSIN ASDGPDRDVY CRTCYGKKWG PHGYGFACGS GFLQTDGLTE 300
  301 DQISANRPFY NPDTTSIKAR DGEGCPRCGG AVFAAEQQLS KGKVWHKKCY NCADCHRPLD 360
  361 SVLACDGPDG DIHCRACYGK LFGPKGFGYG HAPTLVSTSG ESTIQFPDGR PLAGPKTSGG 420
  421 CPRCGFAVFA AEQMISKTRI WHKRCFYCSD CRKSLDSTNL NDGPDGDIYC RACYGRNFGP 480
  481 KGVGYGLGAG ALTTF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
binding	3.10743787485868	bayes_pls_golite062009
transcription regulator activity	2.9286072149962	bayes_pls_golite062009
DNA binding	2.91902554182176	bayes_pls_golite062009
nucleic acid binding	2.84809232393523	bayes_pls_golite062009
cytoskeletal protein binding	2.22104591928521	bayes_pls_golite062009
transcription activator activity	2.18185767124518	bayes_pls_golite062009
protein binding	2.05530362750351	bayes_pls_golite062009
transcription factor activity	2.01262882344347	bayes_pls_golite062009
sequence-specific DNA binding	1.39839669257043	bayes_pls_golite062009
chromatin binding	1.24664529610294	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.11260773303318	bayes_pls_golite062009
structure-specific DNA binding	0.93314267845352	bayes_pls_golite062009
tubulin binding	0.744315484113484	bayes_pls_golite062009
transcription repressor activity	0.587070313263399	bayes_pls_golite062009
microtubule binding	0.576452165256057	bayes_pls_golite062009
metal ion binding	0.571385009230828	bayes_pls_golite062009
cation binding	0.571385009230828	bayes_pls_golite062009
ion binding	0.564805140353876	bayes_pls_golite062009
double-stranded DNA binding	0.53991278722671	bayes_pls_golite062009
transition metal ion binding	0.495045338513967	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.47431986827149	bayes_pls_golite062009
transcription factor binding	0.44682958253968	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..205]	PSI-BLAST	44.522879	No description for 2i13A was found.
2	View Details	[206..348]	PSI-BLAST	15.0	Ying-yang 1 (yy1, zinc finger domain)
3	View Details	[349..495]	PSI-BLAST	14.39794	Five-finger GLI1

Protein Overview: Mlp84B-PA, Mlp84B-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: