Protein Overview: ksr-PA, FBpp0310...

General Information:
Name(s) found:	FBpp0310679 [FlyBase] FBpp0310678 [FlyBase] FBpp0310677 [FlyBase] ksr-PA / FBpp0078413 [FlyBase]
Description(s) found: Found 50 descriptions. SHOW ALL	type=protein; loc=3R:complement(1306459..1309359); ID=FBpp0310679; name=ksr-PD; parent=FBgn0015402,FBtr0344274; dbxref=FlyBase:FBpp0310679,FlyBase_Annotation_IDs:CG2899-PD; MD5=0e5773e280242d6041513eea3a5a7681; length=966; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=3R:complement(1306459..1309359); ID=FBpp0310678; name=ksr-PC; parent=FBgn0015402,FBtr0344273; dbxref=FlyBase:FBpp0310678,FlyBase_Annotation_IDs:CG2899-PC; MD5=0e5773e280242d6041513eea3a5a7681; length=966; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=3R:complement(1306459..1309359); ID=FBpp0310677; name=ksr-PB; parent=FBgn0015402,FBtr0344272; dbxref=FlyBase:FBpp0310677,FlyBase_Annotation_IDs:CG2899-PB; MD5=0e5773e280242d6041513eea3a5a7681; length=966; release=r5.56; species=Dmel; [FlyBase] The gene kinase suppressor of ras is referred to in FlyBase by the symbol Dmel\ksr (CG2899, FBgn0015402). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1305871..1309607. It has the cytological map location 83A5. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase activity; diacylglycerol binding; protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: Ras protein signal transduction; tracheal outgrowth, open tracheal system; imaginal disc-derived wing morphogenesis; signal transduction. 41 alleles are reported. The phenotypes of these alleles are annotated with: eye; photoreceptor cell; eye photoreceptor cell; wing; ommatidium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	966 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	torso signaling pathway [NAS] anterior/posterior axis specification, embryo [TAS] signal transduction [IDA] imaginal disc-derived wing morphogenesis [IMP] Ras protein signal transduction [IGI] protein amino acid phosphorylation [IEA][NAS] tracheal outgrowth, open tracheal system [IMP]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [IEA] diacylglycerol binding [ISS] protein kinase activity [ISS][NAS] protein serine/threonine kinase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNNNAPAS APDTGSTNAN DPISGSLSVD SNLVIIQDMI DLSANHLEGL RTQCAISSTL  60
   61 TQQEIRCLES KLVRYFSELL LAKMRLNERI PANGLVPHTT GNELRQWLRV VGLSQGTLTA 120
  121 CLARLTTLEQ SLRLSDEEIR QLLADSPSQR EEEELRRLTR AMQNLRKCME SLESGTAASN 180
  181 NDPEQWHWDS WDRPTHIHRG SVGNIGLGNN STASPRTHHR QHGVKGKNSA LANSTNFKSG 240
  241 RQSPSATEEL NSTQGSQLTL TLTPSPPNSP FTPSSGLSSS LNGTPQRSRG TPPPARKHQT 300
  301 LLSQSHVQVD GEQLARNRLP TDPSPDSHSS TSSDIFVDPN TNASSGGSSS NVLMVPCSPG 360
  361 VGHVGMGHAI KHRFTKALGF MATCTLCQKQ VFHRWMKCTD CKYICHKSCA PHVPPSCGLP 420
  421 REYVDEFRHI KEQGGYASLP HVHGAAKGSP LVKKSTLGKP LHQQHGDSSS PSSSCTSSTP 480
  481 SSPALFQQRE RELDQAGSSS SANLLPTPSL GKHQPSQFNF PNVTVTSSGG SGGVSLISNE 540
  541 PVPEQFPTAP ATANGGLDSL VSSSNGHMSS LIGSQTSNAS TAATLTGSLV NSTTTTSTCS 600
  601 FFPRKLSTAG VDKRTPFTSE YTDTHKSNDS DKTVSLSGSA STDSDRTPVR VDSTEDGDSG 660
  661 QWRQNSISLK EWDIPYGDLL LLERIGQGRF GTVHRALWHG DVAVKLLNED YLQDEHMLET 720
  721 FRSEVANFKN TRHENLVLFM GACMNPPYLA IVTSLCKGNT LYTYIHQRRE KFAMNRTLLI 780
  781 AQQIAQGMGY LHAREIIHKD LRTKNIFIEN GKVIITDFGL FSSTKLLYCD MGLGVPHNWL 840
  841 CYLAPELIRA LQPEKPRGEC LEFTPYSDVY SFGTVWYELI CGEFTFKDQP AESIIWQVGR 900
  901 GMKQSLANLQ SGRDVKDLLM LCWTYEKEHR PQFARLLSLL EHLPKKRLAR SPSHPVNLSR 960
  961 SAESVF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
binding	2.79128751898373	bayes_pls_golite062009
GTPase regulator activity	2.70614727793157	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	2.68579854252375	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	2.06038764955701	bayes_pls_golite062009
enzyme regulator activity	1.9750017471254	bayes_pls_golite062009
small GTPase regulator activity	1.95738547986197	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.76952905409847	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.65104526054036	bayes_pls_golite062009
protein kinase activity	1.62921423829738	bayes_pls_golite062009
kinase activity	1.56666023161051	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.52955027516214	bayes_pls_golite062009
protein binding	1.29100556128076	bayes_pls_golite062009
signal transducer activity	1.25507073225414	bayes_pls_golite062009
molecular transducer activity	1.25507073225414	bayes_pls_golite062009
Ras GTPase activator activity	1.09070479183477	bayes_pls_golite062009
transcription regulator activity	1.08577758274384	bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity	0.958295643211986	bayes_pls_golite062009
protein serine/threonine kinase activity	0.956859696337723	bayes_pls_golite062009
transferase activity	0.751543629515057	bayes_pls_golite062009
GTPase activator activity	0.717730683557543	bayes_pls_golite062009
nucleic acid binding	0.604021689968387	bayes_pls_golite062009
DNA binding	0.418154636457321	bayes_pls_golite062009
enzyme activator activity	0.298334474872045	bayes_pls_golite062009
catalytic activity	0.194464246602439	bayes_pls_golite062009

Term	Confidence	Notes
binding	3.06905798270146	bayes_pls_golite062009
protein binding	2.08632303609243	bayes_pls_golite062009
signal transducer activity	1.34867629228264	bayes_pls_golite062009
molecular transducer activity	1.34867629228264	bayes_pls_golite062009
cytoskeletal protein binding	0.83493091348808	bayes_pls_golite062009
receptor binding	0.351326788023913	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..186]	MSA	1.074964	View MSA. No confident structure predictions are available.
2	View Details	[187..345]	deduced	N/A	No confident structure predictions are available.
3	View Details	[346..450]	PSI-BLAST	4.69897	Crystal Structure of the Human Beta2-Chimaerin
4	View Details	[451..647]	PSI-BLAST	14.154902	Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas
5	View Details	[648..966]	PSI-BLAST	63.221849	No description for 2fb8A was found.

Protein Overview: ksr-PA, FBpp0310...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: