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Protein Overview: CG6370-PA

General Information:
Name(s) found: CG6370-PA / FBpp0088527 [FlyBase]
Description(s) found:
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  • gi|7302715|gb|AAF57793.1| CG6370 [Drosophila melanogaster] [NCBI NR]
  • gi|19922486|ref|NP_611265.1| CG6370 [Drosophila melanogaster] [NCBI NR]
  • gi|17862258|gb|AAL39606.1| LD18774p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6370 (CG6370, FBgn0034277). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13652077..13654712. It has the cytological map location 54E8. Based on sequence similarity, it is predicted to have molecular function</span>: dolichyl-diphosphooligosaccharide-protein glycotransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: protein amino acid N-linked glycosylation via asparagine. 14 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6370-PA translation from_gene[CG6370 CG6370 FBgn0034277] seq_release:3 mol_weight=69231 cds_boundaries:(2R:12,828,409..12,830,606[-]) aa_length:634 transcript_info:[CG6370-RA seq_release:3] gene_info:[gene symbol:CG6370 FBgn0034277 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V882) CG6370 protein (LD18774p) [DrosMelano7227.FASTAC.txt]
  • (AE003802) CG6370 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG6370-PA [Drosophila melanogaster]gi|17862258|gb|AAL39606.1| LD18774p [Drosophila melanogaster]gi|19922486|ref|NP_611265.1| CG6370-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(13652186..13652556,13652616..13653897,13653966..13654204,13654374..13654386); ID=FBpp0088527; name=CG6370-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1 [fly-100309-contam.fasta]
  • LD18774p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG6370-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(13652186..13652556,13652616..13653897,13653966..13654204,13654374..13654386); ID=FBpp0088527; name=CG6370-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(13652186..13652556,13652616..13653897,13653966..13654204,13654374..13654386); ID=FBpp0088527; name=CG6370-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG6370 OS=Drosophila melanogaster GN=CG6370 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(13652186..13652556,13652616..13653897,13653966..13654204,13654374..13654386); ID=FBpp0088527; name=CG6370-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793,FlyMine:FBpp0088527,modMine:FBpp0088527; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG6370 OS=Drosophila melanogaster GN=CG6370 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:complement(join(17766869..17766881,17766461..17766699,17765111..17766392,17764681..17765051)); ID=FBpp0088527; name=OstDelta-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793,FlyMine:FBpp0088527,modMine:FBpp0088527; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(17766869..17766881,17766461..17766699,17765111..17766392,17764681..17765051)); ID=FBpp0088527; name=OstDelta-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793,FlyMine:FBpp0088527,modMine:FBpp0088527; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • LD18774p OS=Drosophila melanogaster GN=OstDelta PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0088527 type=protein; loc=2R:complement(join(17766869..17766881,17766461..17766699,17765111..17766392,17764681..17765051)); ID=FBpp0088527; name=OstDelta-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793,FlyMine:FBpp0088527,modMine:FBpp0088527; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(17766869..17766881,17766461..17766699,17765111..17766392,17764681..17765051)); ID=FBpp0088527; name=OstDelta-PA; parent=FBgn0034277,FBtr0089559; dbxref=FlyBase:FBpp0088527,FlyBase_Annotation_IDs:CG6370-PA,GB_protein:AAF57793.1,REFSEQ:NP_611265,GB_protein:AAF57793,UniProt/TrEMBL:Q7K110,FlyMine:FBpp0088527,modMine:FBpp0088527; MD5=d380feff7e3062c77891aeaf26ca8028; length=634; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 634 amino acids

    Gene Ontology:
    Cellular Component: oligosaccharyltransferase complex [IEA]
    Biological Process: protein amino acid N-linked glycosylation via asparagine [IEA]
    Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKLGLVIFC VLVASGPTWS ARTVDSHLGQ KDLSRLQKVF VDGFGSSDLQ SIFFSSLNIQ  60
   61 LTDATQKEPL CKKIATLHSE SKLNSFEKDY YYIGASRNLG CSAKIDEGLL SKVYSSLNSE 120
  121 LGSSQEIFYR VVTHKVLGVE INEATQEKLV KRLQELLKKD DTLSGLGYAF NVAPLLGASA 180
  181 SFIANRVEDA IVQADEVDGK LLQFEGGLSI TSLIINGAFG VSKTFNKPVP ITADQAVKFA 240
  241 NYFLSRRSVQ TAKGAHVLIE ALKTISGADK IAPVCVQLIG NGQLDAQSPT LNVAVVDLLG 300
  301 KPLSPAPKVI NAKVIRKKDS SVLADKITVA SKSSDKTTYV ADLASLKPAR GVYQAELSAD 360
  361 GVYTQTLQFK VLGRVKVQSL EVGIAESDAS AATRKQSVTY PGKLQEVLSA DSTQKLLLKA 420
  421 VLVDESTSKP LAVHQAFVRL YNKKTDKEII FVAEQDSSKA YKFDMDVGNN GKNFNYQSGT 480
  481 YSIYLTVGDS SLSNSFEWLV AEVQLKFNED KEVKPKNTSG PLPEIIHQFR VPDKRPPRIV 540
  541 SDIFTGLCIT PLVLLFVFWG KLGINVSNLT LAPSTIGFHL GFGGILVLFF VFWLQLNMFQ 600
  601 TLRLLIPIAV FTFLAGNRLL RRLYAQRNSK ASAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..336] FFAS03 1.02 Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate
    2 View Details [337..496] MSA 1.038967 View MSA. No confident structure predictions are available.
    3 View Details [497..634] MSA 5.045985 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein prenyltransferase activity
    		•  1.8736596502344 bayes_pls_golite062009
  • protein geranylgeranyltransferase activity
    		•  1.36178521139792 bayes_pls_golite062009
  • binding
    		•  0.695640628560574 bayes_pls_golite062009
  • catalytic activity
    		•  0.489632510747336 bayes_pls_golite062009
  • protein binding
    		•  0.434736529133912 bayes_pls_golite062009
  • transferase activity
    		•  0.324269689643948 bayes_pls_golite062009
  • Rab geranylgeranyltransferase activity
    		•  0.147607748607409 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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